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Q6FH65

- Q6FH65_HUMAN

UniProt

Q6FH65 - Q6FH65_HUMAN

Protein
Submitted name:

CSF3 protein

Gene

CSF3

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. immune response Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CSF3 proteinImported
    Submitted name:
    Colony stimulating factor 3 (Granulocyte), isoform CRA_cImported
    Submitted name:
    cDNA, FLJ94067, Homo sapiens colony stimulating factor 3 (granulocyte) (CSF3),transcript variant 2, mRNAImported
    Gene namesi
    Name:CSF3Imported
    ORF Names:hCG_30013Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA26941.

    Protein family/group databases

    Allergomei8367. Hom s G-CSF.

    Structurei

    3D structure databases

    SMRiQ6FH65. Positions 34-204.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000015371.
    HOVERGENiHBG005411.
    KOiK05423.

    Family and domain databases

    Gene3Di1.20.1250.10. 1 hit.
    InterProiIPR009079. 4_helix_cytokine-like_core.
    IPR012351. 4_helix_cytokine_core.
    IPR003573. IL-6/IL-23/GCSF/MGF.
    [Graphical view]
    PfamiPF00489. IL6. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001935. IL6_MGF_GCSF. 1 hit.
    PRINTSiPR00433. IL6GCSFMGF.
    SMARTiSM00126. IL6. 1 hit.
    [Graphical view]
    SUPFAMiSSF47266. SSF47266. 1 hit.
    PROSITEiPS00254. INTERLEUKIN_6. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6FH65-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ    50
    VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ 100
    LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ 150
    MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH 200
    LAQP 204
    Length:204
    Mass (Da):21,978
    Last modified:May 10, 2005 - v1
    Checksum:i5F07C52F13D6A6D3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei204 – 2041Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK313509 mRNA. Translation: BAG36289.1.
    CR541891 mRNA. Translation: CAG46689.1.
    CH471152 Genomic DNA. Translation: EAW60628.1.
    RefSeqiNP_757373.1. NM_172219.2.
    UniGeneiHs.2233.

    Genome annotation databases

    GeneIDi1440.
    KEGGihsa:1440.
    UCSCiuc002hto.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK313509 mRNA. Translation: BAG36289.1 .
    CR541891 mRNA. Translation: CAG46689.1 .
    CH471152 Genomic DNA. Translation: EAW60628.1 .
    RefSeqi NP_757373.1. NM_172219.2.
    UniGenei Hs.2233.

    3D structure databases

    SMRi Q6FH65. Positions 34-204.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 8367. Hom s G-CSF.

    Protocols and materials databases

    DNASUi 1440.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1440.
    KEGGi hsa:1440.
    UCSCi uc002hto.3. human.

    Organism-specific databases

    CTDi 1440.
    PharmGKBi PA26941.

    Phylogenomic databases

    HOGENOMi HOG000015371.
    HOVERGENi HBG005411.
    KOi K05423.

    Miscellaneous databases

    GenomeRNAii 1440.
    NextBioi 5893.

    Family and domain databases

    Gene3Di 1.20.1250.10. 1 hit.
    InterProi IPR009079. 4_helix_cytokine-like_core.
    IPR012351. 4_helix_cytokine_core.
    IPR003573. IL-6/IL-23/GCSF/MGF.
    [Graphical view ]
    Pfami PF00489. IL6. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001935. IL6_MGF_GCSF. 1 hit.
    PRINTSi PR00433. IL6GCSFMGF.
    SMARTi SM00126. IL6. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47266. SSF47266. 1 hit.
    PROSITEi PS00254. INTERLEUKIN_6. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE.
    4. "NEDO functional analysis of protein and research application project."
      Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
      Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.

    Entry informationi

    Entry nameiQ6FH65_HUMAN
    AccessioniPrimary (citable) accession number: Q6FH65
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.