Q6FH65 (Q6FH65_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CSF3 protein EMBL CAG46689.1

Submitted name:
Colony stimulating factor 3 (Granulocyte), isoform CRA_c EMBL EAW60628.1
Submitted name:
cDNA, FLJ94067, Homo sapiens colony stimulating factor 3 (granulocyte) (CSF3),transcript variant 2, mRNA EMBL BAG36289.1

Gene names

Name:	CSF3 EMBL CAG46689.1
ORF Names:	hCG_30013 EMBL EAW60628.1

Organism

Homo sapiens (Human) EMBL CAG46689.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	204 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	204	1	EMBL CAG46689.1

Sequences

	Sequence		Length	Mass (Da)
	Q6FH65 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 5F07C52F13D6A6D3	FASTA	204	21,978
	10 20 30 40 50 60 MAGPATQSPM KLMALQLLLW HSALWTVQEA TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA 70 80 90 100 110 120 LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ 130 140 150 160 170 180 ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG 190 200 VLVASHLQSF LEVSYRVLRH LAQP

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Lung EMBL BAG36289.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK313509 mRNA. Translation: BAG36289.1. CR541891 mRNA. Translation: CAG46689.1. CH471152 Genomic DNA. Translation: EAW60628.1.
IPI	IPI00172503.
RefSeq	NP_757373.1. NM_172219.2.
UniGene	Hs.2233.
3D structure databases
ProteinModelPortal	Q6FH65.
SMR	Q6FH65. Positions 34-204.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FH65.
Protein family/group databases
Allergome	8367. Hom s G-CSF.
Proteomic databases
PRIDE	Q6FH65.
Protocols and materials databases
DNASU	1440.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1440.
KEGG	hsa:1440.
UCSC	uc002hto.3. human.
Organism-specific databases
CTD	1440.
PharmGKB	PA26941.
Phylogenomic databases
HOGENOM	HOG000015371.
HOVERGEN	HBG005411.
KO	K05423.
OrthoDB	EOG4SBDZV.
Gene expression databases
ArrayExpress	Q6FH65.
Bgee	Q6FH65.
Family and domain databases
Gene3D	1.20.1250.10. 1 hit.
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR012351. 4_helix_cytokine_core. IPR003573. IL6_MGF_GCSF. [Graphical view]
Pfam	PF00489. IL6. 1 hit. [Graphical view]
PIRSF	PIRSF001935. IL6_MGF_GCSF. 1 hit.
PRINTS	PR00433. IL6GCSFMGF.
SMART	SM00126. IL6. 1 hit. [Graphical view]
SUPFAM	SSF47266. 4_helix_cytokine. 1 hit.
PROSITE	PS00254. INTERLEUKIN_6. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	1440.
NextBio	5893.

Entry information

Entry name

Q6FH65_HUMAN

Accession

Primary (citable) accession number: Q6FH65

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	March 6, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.