Q6FH62 (Q6FH62_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
HSD17B3 protein EMBL CAG46692.1

Submitted name:
Hydroxysteroid (17-beta) dehydrogenase 3 EMBL CAH71615.1

Gene names

Name:	HSD17B3 EMBL CAG46692.1
ORF Names:	hCG_33005 EMBL EAW92645.1, RP11-240L7.3-005 EMBL CAH71615.1

Organism

Homo sapiens (Human) EMBL CAG46692.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family. RuleBase RU000363

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004267
Gene Ontology (GO)
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6FH62 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 0643FF35ED979185	FASTA	310	34,516
	10 20 30 40 50 60 MGDVLEQFFI LTGLLVCLAC LAKCVRFSRC VLLNYWKVLP KSFLRSMGQW AVITGAGDGI 70 80 90 100 110 120 GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV KIIQADFTKD DIYEHIKEKL 130 140 150 160 170 180 AGLEIGILVN NVGMLPNLLP SHFLNAPDEI QSLIHCNITS VVKMTQLILK HMESRQKGLI 190 200 210 220 230 240 LNISSGIALF PWPLYSMYSA SKAFVCAFSK ALQEEYKAKE VIIQVLTPYA VSTAMTKYLN 250 260 270 280 290 300 TNVITKTADE FVKESLNYVT IGGETCGCLA HEILAGFLSL IPAWAFYSGA FQRLLLTHYV 310 AYLKLNTKVR

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Kimberley A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR541894 mRNA. Translation: CAG46692.1. AL160269 Genomic DNA. Translation: CAH71615.1. CH471174 Genomic DNA. Translation: EAW92645.1.
IPI	IPI00019871.
RefSeq	NP_000188.1. NM_000197.1.
UniGene	Hs.477.
3D structure databases
ProteinModelPortal	Q6FH62.
SMR	Q6FH62. Positions 47-262.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FH62.
Proteomic databases
PRIDE	Q6FH62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3293.
KEGG	hsa:3293.
NMPDR	fig|9606.3.peg.31596.
Organism-specific databases
CTD	3293.
Phylogenomic databases
GeneTree	ENSGT00390000010069.
HOVERGEN	HBG005478.
OMA	SRRKGLI.
PhylomeDB	Q6FH62.
Gene expression databases
ArrayExpress	Q6FH62.
Bgee	Q6FH62.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K10207.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	13063.

Entry information

Entry name

Q6FH62_HUMAN

Accession

Primary (citable) accession number: Q6FH62

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.