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Protein
Submitted name:

DCN protein

Gene

DCN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DCN proteinImported
Submitted name:
Decorin isoform 1Imported
Submitted name:
Decorin, isoform CRA_bImported
Submitted name:
Putative uncharacterized protein DKFZp686J19238Imported
Submitted name:
cDNA FLJ75936, highly similar to Homo sapiens decorin (DCN), transcript variant A1, mRNAImported
Gene namesi
Name:DCNImported
Synonyms:DKFZp686J19238Imported
ORF Names:hCG_24110Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27177.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 359343Sequence analysisPRO_5007708306Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi54 ↔ 60UniRule annotation
Disulfide bondi58 ↔ 67UniRule annotation
Disulfide bondi313 ↔ 346UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Expressioni

Gene expression databases

BgeeiENSG00000011465.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000052754.

Structurei

3D structure databases

SMRiQ6FH10. Positions 51-355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 8533LRRNTInterPro annotationAdd
BLAST

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOVERGENiHBG016052.
KOiK04660.
OMAiPLGPVCP.
OrthoDBiEOG091G044B.
PhylomeDBiQ6FH10.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR028549. Decorin.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRRNT.
IPR016352. SLRP_I_decor/aspor/byglycan.
[Graphical view]
PANTHERiPTHR24369:SF5. PTHR24369:SF5. 1 hit.
PfamiPF13855. LRR_8. 3 hits.
PF01462. LRRNT. 1 hit.
[Graphical view]
PIRSFiPIRSF002490. SLRP_I. 1 hit.
SMARTiSM00369. LRR_TYP. 6 hits.
SM00013. LRRNT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FH10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKATIILLLL AQVSWAGPFQ QRGLFDFMLE DEASGIGPEV PDDRDFEPSL
60 70 80 90 100
GPVCPFRCQC HLRVVQCSDL GLDKVPKDLP PDTTLLDLQN NKITEIKDGD
110 120 130 140 150
FKNLKNLHAL ILVNNKISKV SPGAFTPLVK LERLYLSKNQ LKELPEKMPK
160 170 180 190 200
TLQELRAHEN EITKVRKVTF NGLNQMIVIE LGTNPLKSSG IENGAFQGMK
210 220 230 240 250
KLSYIRIADT NITSIPQGLP PSLTELHLDG NKISRVDAAS LKGLNNLAKL
260 270 280 290 300
GLSFNSISAV DNGSLANTPH LRELHLDNNK LTRVPGGLAE HKYIQVVYLH
310 320 330 340 350
NNNISVVGSS DFCPPGHNTK KASYSGVSLF SNPVQYWEIQ PSTFRCVYVR

SAIQLGNYK
Length:359
Mass (Da):39,747
Last modified:May 10, 2005 - v1
Checksum:iFF511E871A1A52DD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei359 – 3591Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178017 mRNA. Translation: ALQ33475.1.
AK291309 mRNA. Translation: BAF83998.1.
BX571756 mRNA. Translation: CAE11881.1.
CR407676 mRNA. Translation: CAG28604.1.
CR541946 mRNA. Translation: CAG46744.1.
CH471054 Genomic DNA. Translation: EAW97451.1.
CH471054 Genomic DNA. Translation: EAW97452.1.
CH471054 Genomic DNA. Translation: EAW97457.1.
CH471054 Genomic DNA. Translation: EAW97459.1.
RefSeqiNP_001911.1. NM_001920.4.
NP_598010.1. NM_133503.3.
NP_598011.1. NM_133504.3.
NP_598012.1. NM_133505.3.
NP_598013.1. NM_133506.3.
NP_598014.1. NM_133507.3.
XP_005268750.1. XM_005268693.1.
XP_006719333.1. XM_006719270.1.
UniGeneiHs.156316.
Hs.530910.

Genome annotation databases

GeneIDi1634.
KEGGihsa:1634.
UCSCiuc001tbt.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU178017 mRNA. Translation: ALQ33475.1.
AK291309 mRNA. Translation: BAF83998.1.
BX571756 mRNA. Translation: CAE11881.1.
CR407676 mRNA. Translation: CAG28604.1.
CR541946 mRNA. Translation: CAG46744.1.
CH471054 Genomic DNA. Translation: EAW97451.1.
CH471054 Genomic DNA. Translation: EAW97452.1.
CH471054 Genomic DNA. Translation: EAW97457.1.
CH471054 Genomic DNA. Translation: EAW97459.1.
RefSeqiNP_001911.1. NM_001920.4.
NP_598010.1. NM_133503.3.
NP_598011.1. NM_133504.3.
NP_598012.1. NM_133505.3.
NP_598013.1. NM_133506.3.
NP_598014.1. NM_133507.3.
XP_005268750.1. XM_005268693.1.
XP_006719333.1. XM_006719270.1.
UniGeneiHs.156316.
Hs.530910.

3D structure databases

SMRiQ6FH10. Positions 51-355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000052754.

Protocols and materials databases

DNASUi1634.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1634.
KEGGihsa:1634.
UCSCiuc001tbt.4. human.

Organism-specific databases

CTDi1634.
PharmGKBiPA27177.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOVERGENiHBG016052.
KOiK04660.
OMAiPLGPVCP.
OrthoDBiEOG091G044B.
PhylomeDBiQ6FH10.

Miscellaneous databases

ChiTaRSiDCN. human.
GenomeRNAii1634.

Gene expression databases

BgeeiENSG00000011465.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR028549. Decorin.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR000372. LRRNT.
IPR016352. SLRP_I_decor/aspor/byglycan.
[Graphical view]
PANTHERiPTHR24369:SF5. PTHR24369:SF5. 1 hit.
PfamiPF13855. LRR_8. 3 hits.
PF01462. LRRNT. 1 hit.
[Graphical view]
PIRSFiPIRSF002490. SLRP_I. 1 hit.
SMARTiSM00369. LRR_TYP. 6 hits.
SM00013. LRRNT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 8 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FH10_HUMAN
AccessioniPrimary (citable) accession number: Q6FH10
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.