Q6FH10 (Q6FH10_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DCN protein EMBL CAG46744.1

Submitted name:
Decorin, isoform CRA_b EMBL EAW97451.1
Submitted name:
Putative uncharacterized protein DKFZp686J19238 EMBL CAE11881.1
Submitted name:
cDNA FLJ75936, highly similar to Homo sapiens decorin (DCN), transcript variant A1, mRNA EMBL BAF83998.1

Gene names

Name:	DCN EMBL CAG46744.1
Synonyms:	DKFZp686J19238 EMBL CAE11881.1
ORF Names:	hCG_24110 EMBL EAW97451.1

Organism

Homo sapiens (Human) EMBL CAG46744.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	359 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Leucine-rich repeat SAAS SAAS000372 Repeat SAAS SAAS000372
Gene Ontology (GO)
Biological_process	aging Inferred from electronic annotation. Source: Compara kidney development Inferred from electronic annotation. Source: Compara peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan Inferred from electronic annotation. Source: Compara placenta development Inferred from electronic annotation. Source: Compara response to lipopolysaccharide Inferred from electronic annotation. Source: Compara response to mechanical stimulus Inferred from electronic annotation. Source: Compara skeletal muscle tissue development Inferred from electronic annotation. Source: Compara wound healing Inferred from electronic annotation. Source: Compara
Cellular_component	collagen type VI Inferred from electronic annotation. Source: Compara
Molecular_function	extracellular matrix binding Inferred from electronic annotation. Source: Compara glycosaminoglycan binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	359	1	EMBL CAG28604.1

Sequences

	Sequence		Length	Mass (Da)
	Q6FH10 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: FF511E871A1A52DD	FASTA	359	39,747
	10 20 30 40 50 60 MKATIILLLL AQVSWAGPFQ QRGLFDFMLE DEASGIGPEV PDDRDFEPSL GPVCPFRCQC 70 80 90 100 110 120 HLRVVQCSDL GLDKVPKDLP PDTTLLDLQN NKITEIKDGD FKNLKNLHAL ILVNNKISKV 130 140 150 160 170 180 SPGAFTPLVK LERLYLSKNQ LKELPEKMPK TLQELRAHEN EITKVRKVTF NGLNQMIVIE 190 200 210 220 230 240 LGTNPLKSSG IENGAFQGMK KLSYIRIADT NITSIPQGLP PSLTELHLDG NKISRVDAAS 250 260 270 280 290 300 LKGLNNLAKL GLSFNSISAV DNGSLANTPH LRELHLDNNK LTRVPGGLAE HKYIQVVYLH 310 320 330 340 350 NNNISVVGSS DFCPPGHNTK KASYSGVSLF SNPVQYWEIQ PSTFRCVYVR SAIQLGNYK

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	The German cDNA Consortium Bahr A., Lauber J., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Small intestine EMBL CAE11881.1.
[4]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Tongue EMBL BAF83998.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK291309 mRNA. Translation: BAF83998.1. BX571756 mRNA. Translation: CAE11881.1. CR407676 mRNA. Translation: CAG28604.1. CR541946 mRNA. Translation: CAG46744.1. CH471054 Genomic DNA. Translation: EAW97451.1.
IPI	IPI00012119.
RefSeq	NP_001911.1. NM_001920.3. NP_598010.1. NM_133503.2. NP_598011.1. NM_133504.2. NP_598012.1. NM_133505.2. NP_598013.1. NM_133506.2. NP_598014.1. NM_133507.2.
UniGene	Hs.706674.
3D structure databases
ProteinModelPortal	Q6FH10.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FH10.
Proteomic databases
PRIDE	Q6FH10.
Protocols and materials databases
DNASU	1634.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1634.
KEGG	hsa:1634.
Organism-specific databases
CTD	1634.
PharmGKB	PA27177.
Phylogenomic databases
HOVERGEN	HBG016052.
KO	K04660.
OMA	PLGPVCP.
PhylomeDB	Q6FH10.
Gene expression databases
ArrayExpress	Q6FH10.
Bgee	Q6FH10.
Family and domain databases
InterPro	IPR001611. Leu-rich_rpt. IPR003591. Leu-rich_rpt_typical-subtyp. IPR000372. LRR-contain_N. IPR016352. SLRP_I_decor/aspor/byglycan. [Graphical view]
Pfam	PF01462. LRRNT. 1 hit. [Graphical view]
PIRSF	PIRSF002490. SLRP_I. 1 hit.
SMART	SM00369. LRR_TYP. 1 hit. SM00013. LRRNT. 1 hit. [Graphical view]
PROSITE	PS51450. LRR. 8 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	DCN. human.
GenomeRNAi	1634.
NextBio	6702.

Entry information

Entry name

Q6FH10_HUMAN

Accession

Primary (citable) accession number: Q6FH10

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.