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Protein
Submitted name:

HPCAL1 protein

Gene

HPCAL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotation, Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HPCAL1 proteinImported
Submitted name:
Hippocalcin-like 1Imported
Submitted name:
Hippocalcin-like 1, isoform CRA_aImported
Submitted name:
Putative uncharacterized protein HPCAL1Imported
Submitted name:
cDNA FLJ78291, highly similar to Homo sapiens hippocalcin-like 1 (HPCAL1), transcript variant 2, mRNAImported
Gene namesi
Name:HPCAL1Imported
ORF Names:hCG_23828Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29418.

PTM / Processingi

Proteomic databases

MaxQBiQ6FGY1.

Expressioni

Gene expression databases

ExpressionAtlasiQ6FGY1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000310749.

Structurei

3D structure databases

SMRiQ6FGY1. Positions 5-185.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 5818EF-handInterPro annotationAdd
BLAST
Domaini60 – 9536EF-handInterPro annotationAdd
BLAST
Domaini96 – 13136EF-handInterPro annotationAdd
BLAST
Domaini144 – 17936EF-handInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0044. Eukaryota.
COG5126. LUCA.
GeneTreeiENSGT00760000118820.
HOVERGENiHBG108179.
OMAiLEIVQXK.
PhylomeDBiQ6FGY1.

Family and domain databases

Gene3Di1.10.238.10. 3 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR028846. Recoverin.
[Graphical view]
PANTHERiPTHR23055. PTHR23055. 1 hit.
PfamiPF13499. EF-hand_7. 1 hit.
PF13833. EF-hand_8. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FGY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKQNSKLRP EVLQDLRENT EFTDHELQEW YKGFLKDCPT GHLTVDEFKK
60 70 80 90 100
IYANFFPYGD ASKFAEHVFR TFDTNGDGTI DFREFIIALS VTSRGKLEQK
110 120 130 140 150
LKWAFSMYDL DGNGYISRSE MLEIVQAIYK MVSSVMKMPE DESTPEKRTD
160 170 180 190
KIFRQMDTNN DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA SQF
Length:193
Mass (Da):22,313
Last modified:May 10, 2005 - v1
Checksum:i87DCE938DCAD5E1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009835 mRNA. Translation: AAP88837.1.
AC007249 Genomic DNA. Translation: AAY15033.1.
AK292280 mRNA. Translation: BAF84969.1.
CR541975 mRNA. Translation: CAG46773.1.
CH471053 Genomic DNA. Translation: EAX00960.1.
CH471053 Genomic DNA. Translation: EAX00961.1.
CH471053 Genomic DNA. Translation: EAX00962.1.
CH471053 Genomic DNA. Translation: EAX00964.1.
CH471053 Genomic DNA. Translation: EAX00965.1.
CH471053 Genomic DNA. Translation: EAX00966.1.
RefSeqiNP_001245286.1. NM_001258357.1.
NP_001245287.1. NM_001258358.1.
NP_001245288.1. NM_001258359.1.
NP_002140.2. NM_002149.3.
NP_602293.1. NM_134421.2.
XP_005246217.1. XM_005246160.1.
XP_005246218.1. XM_005246161.1.
XP_005246219.1. XM_005246162.1.
XP_005246220.1. XM_005246163.1.
XP_011508647.1. XM_011510345.1.
XP_011508648.1. XM_011510346.1.
XP_011508649.1. XM_011510347.1.
XP_011508650.1. XM_011510348.1.
UniGeneiHs.580427.
Hs.741268.

Genome annotation databases

GeneIDi3241.
KEGGihsa:3241.
UCSCiuc002raj.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009835 mRNA. Translation: AAP88837.1.
AC007249 Genomic DNA. Translation: AAY15033.1.
AK292280 mRNA. Translation: BAF84969.1.
CR541975 mRNA. Translation: CAG46773.1.
CH471053 Genomic DNA. Translation: EAX00960.1.
CH471053 Genomic DNA. Translation: EAX00961.1.
CH471053 Genomic DNA. Translation: EAX00962.1.
CH471053 Genomic DNA. Translation: EAX00964.1.
CH471053 Genomic DNA. Translation: EAX00965.1.
CH471053 Genomic DNA. Translation: EAX00966.1.
RefSeqiNP_001245286.1. NM_001258357.1.
NP_001245287.1. NM_001258358.1.
NP_001245288.1. NM_001258359.1.
NP_002140.2. NM_002149.3.
NP_602293.1. NM_134421.2.
XP_005246217.1. XM_005246160.1.
XP_005246218.1. XM_005246161.1.
XP_005246219.1. XM_005246162.1.
XP_005246220.1. XM_005246163.1.
XP_011508647.1. XM_011510345.1.
XP_011508648.1. XM_011510346.1.
XP_011508649.1. XM_011510347.1.
XP_011508650.1. XM_011510348.1.
UniGeneiHs.580427.
Hs.741268.

3D structure databases

SMRiQ6FGY1. Positions 5-185.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000310749.

Proteomic databases

MaxQBiQ6FGY1.

Protocols and materials databases

DNASUi3241.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3241.
KEGGihsa:3241.
UCSCiuc002raj.5. human.

Organism-specific databases

CTDi3241.
PharmGKBiPA29418.

Phylogenomic databases

eggNOGiKOG0044. Eukaryota.
COG5126. LUCA.
GeneTreeiENSGT00760000118820.
HOVERGENiHBG108179.
OMAiLEIVQXK.
PhylomeDBiQ6FGY1.

Miscellaneous databases

ChiTaRSiHPCAL1. human.
GenomeRNAii3241.
NextBioi12899.

Gene expression databases

ExpressionAtlasiQ6FGY1. baseline and differential.

Family and domain databases

Gene3Di1.10.238.10. 3 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR028846. Recoverin.
[Graphical view]
PANTHERiPTHR23055. PTHR23055. 1 hit.
PfamiPF13499. EF-hand_7. 1 hit.
PF13833. EF-hand_8. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiPS00018. EF_HAND_1. 3 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of Homo sapiens BAC clone RP11-320M2."
    Leonard S., Stoneking T., Hotic M., Ketterman M., Jones T.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE.
  6. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  7. Wilson R.K.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  8. Cited for: NUCLEOTIDE SEQUENCE.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ6FGY1_HUMAN
AccessioniPrimary (citable) accession number: Q6FGY1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 11, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.