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Protein
Submitted name:

IL10 protein

Gene

IL10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
IL10 proteinImported
Submitted name:
Interleukin 10Imported
Gene namesi
Name:IL10Imported
ORF Names:hCG_22208Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000136634.5.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29778.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501110086719 – 178Sequence analysisAdd BLAST160

Expressioni

Gene expression databases

BgeeiENSG00000136634.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ6FGW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IYFW. Eukaryota.
ENOG4111PXC. LUCA.
HOVERGENiHBG004110.
KOiK05443.
OMAiPHMLREL.
OrthoDBiEOG091G0Y3M.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR000098. IL-10.
IPR020443. IL-10/19/20/22/24/26_fam.
IPR020423. IL-10_CS.
PfamiView protein in Pfam
PF00726. IL10. 1 hit.
PRINTSiPR01294. INTRLEUKIN10.
SMARTiView protein in SMART
SM00188. IL10. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00520. INTERLEUKIN_10. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FGW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSSALLCCL VLLTGVRASP GQGTQSENSC THFPGNLPNM LRDLRDAFSR
60 70 80 90 100
VKTFFQMKDQ LDNLLLKESL LEDFKGYLGC QALSEMIQFY LEEVMPQAEN
110 120 130 140 150
QDPDIKAHVN SLGENLKTLR LRLRRCHRFL PCENKSKAVE QVKNAFNKLQ
160 170
EKGIYKAMSE FDIFINYIEA YMTMKIRN
Length:178
Mass (Da):20,517
Last modified:May 10, 2005 - v1
Checksum:i6825E9FA4337CDE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC104252 mRNA. Translation: AAI04253.1.
BC104253 mRNA. Translation: AAI04254.1.
DQ217938 Genomic DNA. Translation: ABB01008.1.
GQ405199 Genomic DNA. Translation: ACV30066.1.
CR541993 mRNA. Translation: CAG46790.1.
CH471100 Genomic DNA. Translation: EAW93524.1.
RefSeqiNP_000563.1. NM_000572.2.
UniGeneiHs.193717.

Genome annotation databases

GeneIDi3586.
KEGGihsa:3586.
UCSCiuc001hen.2. human.

Similar proteinsi

Entry informationi

Entry nameiQ6FGW4_HUMAN
AccessioniPrimary (citable) accession number: Q6FGW4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.