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Protein
Submitted name:

PMVK protein

Gene

PMVK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei141ATPUniRule annotation1
Binding sitei170SubstrateUniRule annotation1
Binding sitei171ATPUniRule annotation1
Binding sitei180ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi17 – 23ATPUniRule annotation7

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
PMVK proteinImported
Submitted name:
Phosphomevalonate kinase, isoform CRA_aImported
Submitted name:
Testis tissue sperm-binding protein Li 95mPImported
Submitted name:
cDNA, FLJ93228, Homo sapiens phosphomevalonate kinase (PMVK), mRNAImported
Gene namesi
Name:PMVKImported
ORF Names:hCG_1739272Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000163344.5

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33465

PTM / Processingi

Proteomic databases

MaxQBiQ6FGV9
PRIDEiQ6FGV9

Expressioni

Gene expression databases

BgeeiENSG00000163344
ExpressionAtlasiQ6FGV9 baseline and differential

Structurei

3D structure databases

SMRiQ6FGV9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IZWN Eukaryota
ENOG4111IXB LUCA
HOVERGENiHBG003277
KOiK13273
OMAiNDIKWFR
OrthoDBiEOG091G0PNO

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005919 Pmev_kin_anim
PANTHERiPTHR13101 PTHR13101, 1 hit
PfamiView protein in Pfam
PF04275 P-mevalo_kinase, 1 hit
PIRSFiPIRSF036639 PMK_anim, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR01223 Pmev_kin_anim, 1 hit

Sequencei

Sequence statusi: Fragment.

Q6FGV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLGGAPRL VLLFSGKRKS GKDFVTEALQ SRLGADVCAV LRLSGPLKEQ
60 70 80 90 100
YAQEHGLNFQ RLLDTSTYKE AFRKDMIRWG EEKRQADPGF FCRKIVEGIS
110 120 130 140 150
QPIWLVSDTR RVSDIQWFRE AYGAVTQTVR VVALEQSRQQ RGWVFTPGVD
160 170 180 190
DAESECGLDN FGDFDWVIEN HGVEQRLEEQ LENLIEFIRS RL
Length:192
Mass (Da):21,995
Last modified:May 10, 2005 - v1
Checksum:iD7E720D0DDCCA249
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM005718 mRNA Translation: AEE61315.1
AK312803 mRNA Translation: BAG35661.1
CR541998 mRNA Translation: CAG46795.1
CH471121 Genomic DNA Translation: EAW53177.1
CH471121 Genomic DNA Translation: EAW53178.1
RefSeqiNP_001309940.1, NM_001323011.2
NP_001309941.1, NM_001323012.2
NP_001335625.1, NM_001348696.1
NP_006547.1, NM_006556.3
UniGeneiHs.30954

Genome annotation databases

GeneIDi10654
KEGGihsa:10654
UCSCiuc001ffq.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6FGV9_HUMAN
AccessioniPrimary (citable) accession number: Q6FGV9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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