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Protein
Submitted name:

RAB7, member RAS oncogene family-like 1

Gene

RAB7L1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RAB7, member RAS oncogene family-like 1Imported
Submitted name:
RAB7, member RAS oncogene family-like 1, isoform CRA_aImported
Submitted name:
RAB7L1 proteinImported
Gene namesi
Name:RAB7L1Imported
ORF Names:hCG_19156Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34151.

Expressioni

Gene expression databases

BgeeiENSG00000117280.
ExpressionAtlasiQ6FGU7. baseline and differential.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ6FGU7. 4 interactors.
STRINGi9606.ENSP00000235932.

Structurei

3D structure databases

SMRiQ6FGU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4423. Eukaryota.
ENOG410YITC. LUCA.
HOVERGENiHBG009351.
KOiK07916.
OMAiQERFISM.
OrthoDBiEOG091G0K53.
PhylomeDBiQ6FGU7.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR030697. Rab29.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PANTHERiPTHR24073:SF315. PTHR24073:SF315. 1 hit.
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6FGU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRDHLFKV LVVGDAAVGK TSLVQRYSQD SFSKHYKSTV GVDFALKVLQ
60 70 80 90 100
WSDYEIVRLQ LWDIAGQERF TSMTRLYYRD ASACVIMFDV TNATTFSNSQ
110 120 130 140 150
RWKQDLDSKL TLPNGEPVPC LLLANKCDLS PWAVSRDQID RFSKENGFTG
160 170 180 190 200
WTETSVKENK NINEAMRVLI EKMMRNSTED IMSLSTQGDY INLQTKSSSW

SCC
Length:203
Mass (Da):23,155
Last modified:May 10, 2005 - v1
Checksum:i40E7CAB02446DF97
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei203Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019540 mRNA. Translation: AAV38347.1.
CR542010 mRNA. Translation: CAG46807.1.
CH471067 Genomic DNA. Translation: EAW91580.1.
CH471067 Genomic DNA. Translation: EAW91581.1.
RefSeqiNP_001129134.1. NM_001135662.1.
NP_003920.1. NM_003929.2.
XP_005245626.1. XM_005245569.1.
XP_005245627.1. XM_005245570.1.
XP_005245628.1. XM_005245571.1.
UniGeneiHs.115325.

Genome annotation databases

GeneIDi8934.
KEGGihsa:8934.
UCSCiuc001hde.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019540 mRNA. Translation: AAV38347.1.
CR542010 mRNA. Translation: CAG46807.1.
CH471067 Genomic DNA. Translation: EAW91580.1.
CH471067 Genomic DNA. Translation: EAW91581.1.
RefSeqiNP_001129134.1. NM_001135662.1.
NP_003920.1. NM_003929.2.
XP_005245626.1. XM_005245569.1.
XP_005245627.1. XM_005245570.1.
XP_005245628.1. XM_005245571.1.
UniGeneiHs.115325.

3D structure databases

SMRiQ6FGU7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6FGU7. 4 interactors.
STRINGi9606.ENSP00000235932.

Protocols and materials databases

DNASUi8934.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8934.
KEGGihsa:8934.
UCSCiuc001hde.5. human.

Organism-specific databases

CTDi8934.
PharmGKBiPA34151.

Phylogenomic databases

eggNOGiKOG4423. Eukaryota.
ENOG410YITC. LUCA.
HOVERGENiHBG009351.
KOiK07916.
OMAiQERFISM.
OrthoDBiEOG091G0K53.
PhylomeDBiQ6FGU7.

Miscellaneous databases

ChiTaRSiRAB7L1. human.
GenomeRNAii8934.

Gene expression databases

BgeeiENSG00000117280.
ExpressionAtlasiQ6FGU7. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR030697. Rab29.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PANTHERiPTHR24073:SF315. PTHR24073:SF315. 1 hit.
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FGU7_HUMAN
AccessioniPrimary (citable) accession number: Q6FGU7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: January 18, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.