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Protein
Submitted name:

OPRL1 protein

Gene

OPRL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
OPRL1 proteinImported
Gene namesi
Name:OPRL1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei55 – 77HelicalSequence analysisAdd BLAST23
Transmembranei89 – 107HelicalSequence analysisAdd BLAST19
Transmembranei113 – 132HelicalSequence analysisAdd BLAST20
Transmembranei172 – 191HelicalSequence analysisAdd BLAST20
Transmembranei211 – 239HelicalSequence analysisAdd BLAST29
Transmembranei260 – 279HelicalSequence analysisAdd BLAST20
Transmembranei299 – 322HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ6FGM5.

Structurei

3D structure databases

ProteinModelPortaliQ6FGM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 319G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106919.

Family and domain databases

CDDicd15092. 7tmA_NOFQ_opioid_R. 1 hit.
InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001418. Opioid_rcpt.
IPR001420. X_opioid_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR00384. OPIOIDR.
PR00547. XOPIOIDR.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FGM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPLFPAPFW EVIYGSHLQG NLSLLSPNHS LLPPHLLLNA SHGAFLPLGL
60 70 80 90 100
KVTIVGLYLA VCVGGLLGNC LVMYVILRHT KMKTATNIYI FNLALADTLV
110 120 130 140 150
LLTLPFQGTD ILLGFWPFGN ALCKTVIAID YYNMFTSTFT LTAMSVDRYV
160 170 180 190 200
AICHPIRALD VRTSSKAQAV NVAIWALASV VGVPVAIMGS AQVEDEEIEC
210 220 230 240 250
PVEIPTPQDY WGPVFAICIF LFSFIVPVLV ISVCYSLMIR RLRGVRLLSG
260 270 280 290 300
SREKDRNLRR ITRLVLVVVA VFVGCWTPVQ VFVLAQGLGV QPSSETAVAI
310 320 330 340 350
LRFCTALGYV NSCLNPILYA FLDENFKACF RKFCCASALR RDVQVSDRVR
360 370
SIAKDVALAC KTSETVPRPA
Length:370
Mass (Da):40,677
Last modified:July 19, 2004 - v1
Checksum:iC1388EF7D6FD3FA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR542082 mRNA. Translation: CAG46879.1.
UniGeneiHs.2859.
Hs.736944.

Similar proteinsi

Entry informationi

Entry nameiQ6FGM5_HUMAN
AccessioniPrimary (citable) accession number: Q6FGM5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: August 30, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.