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Protein
Submitted name:

OPRL1 protein

Gene

OPRL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
OPRL1 proteinImported
Gene namesi
Name:OPRL1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei55 – 7723HelicalSequence analysisAdd
BLAST
Transmembranei89 – 10719HelicalSequence analysisAdd
BLAST
Transmembranei113 – 13220HelicalSequence analysisAdd
BLAST
Transmembranei172 – 19120HelicalSequence analysisAdd
BLAST
Transmembranei211 – 23929HelicalSequence analysisAdd
BLAST
Transmembranei260 – 27920HelicalSequence analysisAdd
BLAST
Transmembranei299 – 32224HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ6FGM5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000336764.

Structurei

3D structure databases

ProteinModelPortaliQ6FGM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini68 – 319252G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106919.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001418. Opioid_rcpt.
IPR001420. X_opioid_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00384. OPIOIDR.
PR00547. XOPIOIDR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FGM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPLFPAPFW EVIYGSHLQG NLSLLSPNHS LLPPHLLLNA SHGAFLPLGL
60 70 80 90 100
KVTIVGLYLA VCVGGLLGNC LVMYVILRHT KMKTATNIYI FNLALADTLV
110 120 130 140 150
LLTLPFQGTD ILLGFWPFGN ALCKTVIAID YYNMFTSTFT LTAMSVDRYV
160 170 180 190 200
AICHPIRALD VRTSSKAQAV NVAIWALASV VGVPVAIMGS AQVEDEEIEC
210 220 230 240 250
PVEIPTPQDY WGPVFAICIF LFSFIVPVLV ISVCYSLMIR RLRGVRLLSG
260 270 280 290 300
SREKDRNLRR ITRLVLVVVA VFVGCWTPVQ VFVLAQGLGV QPSSETAVAI
310 320 330 340 350
LRFCTALGYV NSCLNPILYA FLDENFKACF RKFCCASALR RDVQVSDRVR
360 370
SIAKDVALAC KTSETVPRPA
Length:370
Mass (Da):40,677
Last modified:July 19, 2004 - v1
Checksum:iC1388EF7D6FD3FA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR542082 mRNA. Translation: CAG46879.1.
UniGeneiHs.2859.
Hs.736944.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR542082 mRNA. Translation: CAG46879.1.
UniGeneiHs.2859.
Hs.736944.

3D structure databases

ProteinModelPortaliQ6FGM5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000336764.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ6FGM5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106919.

Miscellaneous databases

ChiTaRSiOPRL1. human.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001418. Opioid_rcpt.
IPR001420. X_opioid_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00384. OPIOIDR.
PR00547. XOPIOIDR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6FGM5_HUMAN
AccessioniPrimary (citable) accession number: Q6FGM5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: June 8, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.