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Q6FGL7

- Q6FGL7_HUMAN

UniProt

Q6FGL7 - Q6FGL7_HUMAN

Protein
Submitted name:

FABP1 protein

Gene

FABP1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. bile acid binding Source: Ensembl
    2. chromatin binding Source: Ensembl
    3. drug binding Source: Ensembl
    4. fatty acid binding Source: Ensembl
    5. long-chain fatty acid transporter activity Source: Ensembl
    6. phospholipid binding Source: Ensembl

    GO - Biological processi

    1. intestinal absorption Source: Ensembl
    2. positive regulation of cell proliferation Source: Ensembl
    3. positive regulation of fatty acid beta-oxidation Source: Ensembl
    4. positive regulation of hydrolase activity Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    FABP1 proteinImported
    Submitted name:
    Fatty acid binding protein 1, liver, isoform CRA_bImported
    Submitted name:
    Putative uncharacterized protein FABP1Imported
    Gene namesi
    Name:FABP1Imported
    ORF Names:hCG_32947Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. apical cortex Source: Ensembl
    2. cytosol Source: Ensembl
    3. nucleus Source: Ensembl
    4. peroxisomal matrix Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA27956.

    Structurei

    3D structure databases

    SMRiQ6FGL7. Positions 2-127.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG005633.
    KOiK08750.
    OMAiDTITNTM.
    PhylomeDBiQ6FGL7.

    Family and domain databases

    Gene3Di2.40.128.20. 1 hit.
    InterProiIPR012674. Calycin.
    IPR011038. Calycin-like.
    IPR000463. Fatty_acid-bd.
    [Graphical view]
    PRINTSiPR00178. FATTYACIDBP.
    SUPFAMiSSF50814. SSF50814. 1 hit.
    PROSITEiPS00214. FABP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6FGL7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF    50
    TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS 100
    VTELNGDIIT NTMTLGDIVF KRISKRI 127
    Length:127
    Mass (Da):14,208
    Last modified:May 10, 2005 - v1
    Checksum:i065DCEFB08DAB6B6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei127 – 1271Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC092836 Genomic DNA. Translation: AAX88905.1.
    CR542090 mRNA. Translation: CAG46887.1.
    CH471215 Genomic DNA. Translation: EAW77076.1.
    RefSeqiNP_001434.1. NM_001443.2.
    UniGeneiHs.380135.

    Genome annotation databases

    GeneIDi2168.
    KEGGihsa:2168.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC092836 Genomic DNA. Translation: AAX88905.1 .
    CR542090 mRNA. Translation: CAG46887.1 .
    CH471215 Genomic DNA. Translation: EAW77076.1 .
    RefSeqi NP_001434.1. NM_001443.2.
    UniGenei Hs.380135.

    3D structure databases

    SMRi Q6FGL7. Positions 2-127.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 2168.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2168.
    KEGGi hsa:2168.

    Organism-specific databases

    CTDi 2168.
    PharmGKBi PA27956.

    Phylogenomic databases

    HOVERGENi HBG005633.
    KOi K08750.
    OMAi DTITNTM.
    PhylomeDBi Q6FGL7.

    Miscellaneous databases

    ChiTaRSi FABP1. human.
    GenomeRNAii 2168.
    NextBioi 8755.

    Family and domain databases

    Gene3Di 2.40.128.20. 1 hit.
    InterProi IPR012674. Calycin.
    IPR011038. Calycin-like.
    IPR000463. Fatty_acid-bd.
    [Graphical view ]
    PRINTSi PR00178. FATTYACIDBP.
    SUPFAMi SSF50814. SSF50814. 1 hit.
    PROSITEi PS00214. FABP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The sequence of Homo sapiens BAC clone RP11-50B16."
      Haakenson W., Boyer E., Pearman C.
      Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Waterston R.H.
      Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    4. Waterston R.
      Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    5. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    6. Wilson R.K.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    7. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6FGL7_HUMAN
    AccessioniPrimary (citable) accession number: Q6FGL7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.