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Protein
Submitted name:

TM4SF13 protein

Gene

TM4SF13

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TM4SF13 proteinImported
Submitted name:
Tetraspanin 13, isoform CRA_aImported
Submitted name:
Transmembrane 4 superfamily member 13Imported
Submitted name:
cDNA, FLJ95977, Homo sapiens transmembrane 4 superfamily member 13 (TM4SF13), mRNAImported
Gene namesi
Name:TM4SF13Imported
Synonyms:TSPAN13Imported
ORF Names:hCG_17375Imported, tcag7.1203Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000106537.7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 40HelicalSequence analysisAdd BLAST29
Transmembranei46 – 68HelicalSequence analysisAdd BLAST23
Transmembranei75 – 100HelicalSequence analysisAdd BLAST26
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134868624

PTM / Processingi

Proteomic databases

MaxQBiQ6FGK0

Expressioni

Gene expression databases

BgeeiENSG00000106537
ExpressionAtlasiQ6FGK0 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ6FGK0, 1 interactor

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
HOVERGENiHBG009195
KOiK17356
OMAiTEFVGVW
OrthoDBiEOG091G0PBF

Family and domain databases

InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR

Sequencei

Sequence statusi: Complete.

Q6FGK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCGGFACSK NCLCALNLLY TLVSLLLIGI AAWGIGFGLI SSLRVVGVVI
60 70 80 90 100
AVGIFLFLIA LVGLIGAVKH HQVLLFFYMI ILLLVFIVQF SVSCACLALN
110 120 130 140 150
QEQQGQLLEV GWNNTASARN DIQRNLNCCG FRSVNPNDTC LASCVKSDHS
160 170 180 190 200
CSPCAPIIGE YAGEVLRFVG GIGLFFSFTE ILGVWLTYRY RNQKDPRANP

SAFL
Length:204
Mass (Da):22,147
Last modified:May 10, 2005 - v1
Checksum:i5928646BCD83C0D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316595 mRNA Translation: BAG38182.1
CR542107 mRNA Translation: CAG46904.1
CH236948 Genomic DNA Translation: EAL24284.1
CH471073 Genomic DNA Translation: EAW93680.1
CH471073 Genomic DNA Translation: EAW93681.1
RefSeqiNP_055214.1, NM_014399.3
UniGeneiHs.364544

Genome annotation databases

GeneIDi27075
KEGGihsa:27075
UCSCiuc003stq.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6FGK0_HUMAN
AccessioniPrimary (citable) accession number: Q6FGK0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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