Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutathione S-transferase

Gene

GSTM3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:GSTM3Imported
ORF Names:hCG_40244Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000134202.10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29024

PTM / Processingi

Proteomic databases

MaxQBiQ6FGJ9
PRIDEiQ6FGJ9

Expressioni

Gene expression databases

BgeeiENSG00000134202
ExpressionAtlasiQ6FGJ9 baseline and differential

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ6FGJ9, 2 interactors

Structurei

3D structure databases

SMRiQ6FGJ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 92GST N-terminalInterPro annotationAdd BLAST88
Domaini94 – 212GST C-terminalInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IN5J Eukaryota
ENOG4110YU0 LUCA
HOVERGENiHBG106842
KOiK00799
OMAiDIMENQV
OrthoDBiEOG091G0K2E

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR003081 GST_mu
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
PRINTSiPR01267 GSTRNSFRASEM
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FGJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCESSMVLG YWDIRGLAHA IRLLLEFTDT SYEEKRYTCG EAPDYDRSQW
60 70 80 90 100
LDVKFKLDLD FPNLPYLLDG KNKITQSNAI LRYIARKHNM CGETEEEKIR
110 120 130 140 150
VDIIENQVMD FRTQLIRLCY SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS
160 170 180 190 200
WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD EFPNLKAFMC RFEALEKIAA
210 220
YLQSDQFCKM PINNKMAQWG NKPVC
Length:225
Mass (Da):26,560
Last modified:May 10, 2005 - v1
Checksum:i79093161ECEF5396
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU136188 Genomic DNA Translation: ABV02583.1
AK313444 mRNA Translation: BAG36233.1
CR542108 mRNA Translation: CAG46905.1
CH471122 Genomic DNA Translation: EAW56409.1
RefSeqiNP_000840.2, NM_000849.4
UniGeneiHs.2006

Genome annotation databases

GeneIDi2947
KEGGihsa:2947
UCSCiuc001dyo.3 human

Similar proteinsi

Entry informationi

Entry nameiQ6FGJ9_HUMAN
AccessioniPrimary (citable) accession number: Q6FGJ9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health