Q6FGJ9 (Q6FGJ9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GSTM3 protein EMBL CAG46905.1

Submitted name:
Glutathione S-transferase M3 (Brain) EMBL ABV02583.1
Submitted name:
cDNA, FLJ93985, Homo sapiens glutathione S-transferase M3 (brain) (GSTM3), mRNA EMBL BAG36233.1

Gene names

Name:	GSTM3 EMBL CAG46905.1
ORF Names:	hCG_40244 EMBL EAW56409.1

Organism

Homo sapiens (Human) EMBL CAG46905.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the GST superfamily. RuleBase RU003494 Contains 1 GST C-terminal domain. SAAS SAAS004045 Contains 1 GST N-terminal domain.

Ontologies

Keywords
Molecular function	Transferase EMBL ABV02583.1
Gene Ontology (GO)
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6FGJ9 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 79093161ECEF5396	FASTA	225	26,560
	10 20 30 40 50 60 MSCESSMVLG YWDIRGLAHA IRLLLEFTDT SYEEKRYTCG EAPDYDRSQW LDVKFKLDLD 70 80 90 100 110 120 FPNLPYLLDG KNKITQSNAI LRYIARKHNM CGETEEEKIR VDIIENQVMD FRTQLIRLCY 130 140 150 160 170 180 SSDHEKLKPQ YLEELPGQLK QFSMFLGKFS WFAGEKLTFV DFLTYDILDQ NRIFDPKCLD 190 200 210 220 EFPNLKAFMC RFEALEKIAA YLQSDQFCKM PINNKMAQWG NKPVC

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Rieder M.J., Bertucci C., Stanaway I.B., Johnson E.J., Swanson J.E., Siegel D.L., da Ponte S.H., Igartua C., Patterson K., Nickerson D.A. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Amygdala EMBL BAG36233.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU136188 Genomic DNA. Translation: ABV02583.1. AK313444 mRNA. Translation: BAG36233.1. CR542108 mRNA. Translation: CAG46905.1. CH471122 Genomic DNA. Translation: EAW56409.1.
IPI	IPI00246975.
RefSeq	NP_000840.2. NM_000849.4.
UniGene	Hs.2006.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q6FGJ9.
Protocols and materials databases
DNASU	2947.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2947.
KEGG	hsa:2947.
Organism-specific databases
CTD	2947.
PharmGKB	PA29024.
Phylogenomic databases
HOVERGEN	HBG106842.
KO	K00799.
OMA	MSCESSM.
PhylomeDB	Q6FGJ9.
Gene expression databases
ArrayExpress	Q6FGJ9.
Family and domain databases
Gene3D	1.20.1050.10. 1 hit. 3.40.30.10. 1 hit.
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR003081. GST_mu. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
PRINTS	PR01267. GSTRNSFRASEM.
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	2947.
NextBio	11678.

Entry information

Entry name

Q6FGJ9_HUMAN

Accession

Primary (citable) accession number: Q6FGJ9

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.