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Protein
Submitted name:

VAMP3 protein

Gene

VAMP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
VAMP3 proteinImported
Submitted name:
Vesicle-associated membrane protein 3 (Cellubrevin)Imported
Submitted name:
cDNA, FLJ92013, Homo sapiens vesicle-associated membrane protein 3 (cellubrevin)(VAMP3), mRNAImported
Gene namesi
Name:VAMP3Imported
ORF Names:hCG_21813Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37268.

Expressioni

Gene expression databases

BgeeiENSG00000049245.
ExpressionAtlasiQ6FGG2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000054666.

Structurei

3D structure databases

SMRiQ6FGG2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 74V-SNARE coiled-coil homologyInterPro annotationAdd BLAST61

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0860. Eukaryota.
COG5143. LUCA.
HOVERGENiHBG006675.
KOiK13505.
OMAiFTHACAF.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ6FGG2.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FGG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGPTAATG SNRRLQQTQN QVDEVVDIMR VNVDKVLERD QKLSELDDRA
60 70 80 90 100
DALQAGASQF ETSAAKLKRK YWWKNCKMWA IGITVLVIFI IIIIVWVVSS
Length:100
Mass (Da):11,309
Last modified:May 10, 2005 - v1
Checksum:i347E9163157AFF42
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei100Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316558 mRNA. Translation: BAG38147.1.
CR542145 mRNA. Translation: CAG46942.1.
CR542154 mRNA. Translation: CAG46951.1.
CH471130 Genomic DNA. Translation: EAW71582.1.
RefSeqiNP_004772.1. NM_004781.3.
UniGeneiHs.66708.

Genome annotation databases

GeneIDi9341.
KEGGihsa:9341.
UCSCiuc001aol.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316558 mRNA. Translation: BAG38147.1.
CR542145 mRNA. Translation: CAG46942.1.
CR542154 mRNA. Translation: CAG46951.1.
CH471130 Genomic DNA. Translation: EAW71582.1.
RefSeqiNP_004772.1. NM_004781.3.
UniGeneiHs.66708.

3D structure databases

SMRiQ6FGG2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000054666.

Protocols and materials databases

DNASUi9341.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9341.
KEGGihsa:9341.
UCSCiuc001aol.3. human.

Organism-specific databases

CTDi9341.
PharmGKBiPA37268.

Phylogenomic databases

eggNOGiKOG0860. Eukaryota.
COG5143. LUCA.
HOVERGENiHBG006675.
KOiK13505.
OMAiFTHACAF.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ6FGG2.

Miscellaneous databases

ChiTaRSiVAMP3. human.
GenomeRNAii9341.

Gene expression databases

BgeeiENSG00000049245.
ExpressionAtlasiQ6FGG2. baseline and differential.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FGG2_HUMAN
AccessioniPrimary (citable) accession number: Q6FGG2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: January 18, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.