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Protein

Alanine racemase

Gene

dadX

Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (dadX), Alanine racemase (alr)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei35Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei130SubstrateUniRule annotation1
Active sitei256Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei304Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciASP62977:G1GJ8-107-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dadXImported
Ordered Locus Names:ACIAD0116Imported
OrganismiAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)Imported
Taxonomic identifieri62977 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter
Proteomesi
  • UP000000430 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei35N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi62977.ACIAD0116

Structurei

3D structure databases

ProteinModelPortaliQ6FFR4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini235 – 364Ala_racemase_CInterPro annotationAdd BLAST130

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031446
KOiK01775
OMAiISHFACA
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.10, 2 hits
3.20.20.10, 1 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FFR4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRPIQAVIH LEALAHNLKI VRASAPESQV FAVVKANAYG HGIERVYQAF
60 70 80 90 100
KQADGFALLD IEEAKRLRAL GWTGPILLLE GIFSPQDLFD CVQYQLSFTV
110 120 130 140 150
HHDVQIDWIE GHPEDAQFDI FLKMNSGMNR LGFKPVQYRH AWQRLNALSQ
160 170 180 190 200
VRHLTHMMHF SDADGERFGE SGITYQHDLF EDTIRDLPGP KSVSNSAAIL
210 220 230 240 250
RHPLHSDVVR GGIMLYGSSP DYPTHGLHDW SLKPTMSLRS EIIAIQMLEP
260 270 280 290 300
NESVGYGSSF VADQPLRIGI VACGYADGYQ RISPTGTPVL VDGIETRTIG
310 320 330 340 350
RVSMDMLAVD LSAVPKARIG SEVVLWGYSS TGVILPIDDV AAASGTVGYE
360
LMCAVTARVP FTIQT
Length:365
Mass (Da):40,251
Last modified:July 19, 2004 - v1
Checksum:i63FAF6B3996000BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR543861 Genomic DNA Translation: CAG67093.1
RefSeqiWP_004930719.1, NC_005966.1

Genome annotation databases

EnsemblBacteriaiCAG67093; CAG67093; ACIAD0116
KEGGiaci:ACIAD0116

Similar proteinsi

Entry informationi

Entry nameiQ6FFR4_ACIAD
AccessioniPrimary (citable) accession number: Q6FFR4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: February 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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