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Q6FFQ1 (KDGD_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 5-dehydro-4-deoxyglucarate dehydratase
EC=4.2.1.41
Alternative name(s):
5-keto-4-deoxy-glucarate dehydratase
Short name=KDGDH
Gene names
Ordered Locus Names:ACIAD0130
OrganismAcinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2. HAMAP-Rule MF_00694

Pathway

Carbohydrate acid metabolism; D-glucarate degradation; 2,5-dioxopentanoate from D-glucarate: step 2/2. HAMAP-Rule MF_00694

Sequence similarities

Belongs to the DapA family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-glucarate catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_function5-dehydro-4-deoxyglucarate dehydratase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303Probable 5-dehydro-4-deoxyglucarate dehydratase HAMAP-Rule MF_00694
PRO_1000045396

Sequences

Sequence LengthMass (Da)Tools
Q6FFQ1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 55091529B63A1778

FASTA30332,624
        10         20         30         40         50         60 
MDALELKNIV SDGLLSFPVT DFDQNGDFNA ASYAKRLEWL APYGASALFA AGGTGEFFSL 

        70         80         90        100        110        120 
TGDEYSDVIK TAVDACKGSV PIIAGAGGPT RQAILQAQEA ERLGAHGILL MPHYLTEASQ 

       130        140        150        160        170        180 
EGLVEHVKQV CNAVNFGVIF YNRSVSKLNV DSLQQLVESC PNLIGFKDSS GQIDMMTEVV 

       190        200        210        220        230        240 
QTLGDRLSYL GGLPTAEIFA APYKALGSPV YSSAVFNFIP KTAMEFYNAL RNDDFATTQR 

       250        260        270        280        290        300 
LIRDFFLPLI KIRNRKSGYA VSMVKAGAKI VGHDAGPVRP PLSDLTPQDY EDLAALIATL 


GPQ

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References

[1]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ADP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR543861 Genomic DNA. Translation: CAG67106.1.
RefSeqYP_044928.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ6FFQ1.
ModBaseSearch...

Protein-protein interaction databases

STRING62977.ACIAD0130.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG67106; CAG67106; ACIAD0130.
GeneID2879972.
KEGGaci:ACIAD0130.
PATRIC20738238. VBIAciSp98416_0116.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0329.
HOGENOMHOG000173605.
KOK01707.
OMALTEASQD.
ProtClustDBPRK03620.

Enzyme and pathway databases

BioCycASP62977:GJVV-126-MONOMER.
MetaCyc:MONOMER-15625.
UniPathwayUPA00564; UER00628.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00694. KDGDH.
InterProIPR013785. Aldolase_TIM.
IPR017655. Dehydro-deoxyglucarate_dehyd.
IPR002220. Dihydrodipicolinate_synth-like.
[Graphical view]
PANTHERPTHR12128. PTHR12128. 1 hit.
PfamPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFPIRSF001365. DHDPS. 1 hit.
PRINTSPR00146. DHPICSNTHASE.
TIGRFAMsTIGR03249. KdgD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKDGD_ACIAD
AccessionPrimary (citable) accession number: Q6FFQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 19, 2004
Last modified: May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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