Reviewed, UniProtKB/Swiss-Prot Q6FFM0 (SYR_ACIAD)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	ACIAD0164

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	596 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 596	596	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241973
Regions
	Motif	128 – 138	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q6FFM0-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 5B541365535D241E	FASTA	596	66,918
	10 20 30 40 50 60 MNTAIQAALD HVVQSLQQEG ILPSDWNNNS TLTRTKDRSH GDFASNIAMV GSKAAGMKPR 70 80 90 100 110 120 DLAEKILASL PEVADITKAE IAGPGFINFF LNADQRFAVL DQIQAQGQYY GQTQVNAEKK 130 140 150 160 170 180 IQVEFVSANP TSSLHVGHGR GAAYGMTVAN LLEATGAQVD REYYVNDAGR QMDILATSTY 190 200 210 220 230 240 LRYLELLGQP LVFPKNAYQG DYVKEIAQSI IDKDGDAYVR SVADVYRNVP EDVQYAEELD 250 260 270 280 290 300 SEGNKVVLSG DKEKHIDGLI ANSQQLIGQG YRVFHQAALK AILDDIKDDL ADFGVTFDQW 310 320 330 340 350 360 FSEASLTQKI DEALQTLDQR GYLYEKEGNI WFKSTKFGDE KDRVVKRRNG QTTYFASDIA 370 380 390 400 410 420 YHLDKLQRGY THIVDIWGSD HHGYIARVKA AIDAMGYDSS KLTVLLVQFV SLWRGGEMVQ 430 440 450 460 470 480 MSSRSGQFVT LRELRQEVGN DAARFYYVMR KSEQHIDFDL DLAVSQSKDN AVYYIQYAHA 490 500 510 520 530 540 RICRMLEKAN STQMRFNQTQ ARQFANRLDL DAETEILAKL AAYPDILVRA ANAYEPHQIG 550 560 570 580 590 NYLKELAALF HGWYNEHKVL TEDVELTQAR LLLSVNVQQV LRNGLDLLGV SAPEAM

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR543861 Genomic DNA. Translation: CAG67137.1.
RefSeq	YP_044959.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FFM0.
Genome annotation databases
GeneID	2878784.
GenomeReviews	Gene locus ACIAD0164 in contig CR543861_GR.
KEGG	aci:ACIAD0164.
NMPDR	fig|62977.3.peg.254.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6FFM0.
OMA	ADHHGYV.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD0164-MON.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_ACIAD

Accession

Primary (citable) accession number: Q6FFM0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)