Reviewed, UniProtKB/Swiss-Prot Q6FEQ6 (NTPA_ACIAD)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

ACIAD0526

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 210	210	Nucleoside-triphosphatase HAMAP MF_01405		PRO_0000178114

Sequences

	Sequence		Length	Mass (Da)
	Q6FEQ6-1 [UniParc]. Last modified April 26, 2005. Version 2. Checksum: 93BBAD9E9CB69622	FASTA	210	23,177
	10 20 30 40 50 60 MSAPHWLSQG TLVLASNNKG KITEFEKLFA ELQLPVDVIP QGQLNIPDAI EDGLSFVENA 70 80 90 100 110 120 IIKARHASKI SGKPAIADDS GICVPVLGGA PGIYSARYAG DHGNDAANNE KLLHDLKPFR 130 140 150 160 170 180 NAEQAIQGMF VCVLALVEHA EDPLPQIFQG FWHGEILEQA RGEHGFGYDP LFWLSELKMS 190 200 210 SAEMSKEEKN KISHRGQAMQ RFRESLMTRE

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR543861 Genomic DNA. Translation: CAG67452.1. Different initiation.
RefSeq	YP_045274.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FEQ6.
Genome annotation databases
GeneID	2881010.
GenomeReviews	Gene locus ACIAD0526 in contig CR543861_GR.
KEGG	aci:ACIAD0526.
NMPDR	fig|62977.3.peg.1289.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6FEQ6.
OMA	VYTADWA.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD0526-MON.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
TIGRFAMs	TIGR00042. Ham1p_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NTPA_ACIAD

Accession

Primary (citable) accession number: Q6FEQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	November 3, 2009
This is version 32 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)