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Q6FEP2 (PTA_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:ACIAD0540
OrganismAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length720 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 720720Phosphate acetyltransferase
PRO_0000405544

Regions

Region389 – 720332Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q6FEP2 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 2657B1A8C48606CB

FASTA72077,882
        10         20         30         40         50         60 
MNTILMIPTG EGVGLTSACL GLIYALDCNG IKAGFLKPFS QELPNQVDRT TSLFSHLFQG 

        70         80         90        100        110        120 
KTVTSISHEK VLQRLALGER DELLEEAVSI HRNVAANYDV IIVEGLLPNA QDHFATELNA 

       130        140        150        160        170        180 
ALAQALDAKV VLVSTADVQN PRRTAEKIEA HLHHFGGVSS NRTAGVLFMR TRGLPEETAQ 

       190        200        210        220        230        240 
IPLTIDPSLR LNTEIAAFSQ ELQRYNRNLG TTTLPIIGLV PFSNTLSVPR TLDIASIIEG 

       250        260        270        280        290        300 
DWIHQGEARH RRILHSSLIA SSIEYELNKF VAGELIISAS ERTDVLLASS LATSNGIPLA 

       310        320        330        340        350        360 
GLVLTERKAP NPQILDFCQH AIKQGLPILH TQLNTLETAQ RLADFGNEIP VDDTERAEQV 

       370        380        390        400        410        420 
TRFVSSHIDT AWLNSQINTG VQPRLSPSAF RHELVQKSIA AKKRIVLPEG DEPRTVQAAA 

       430        440        450        460        470        480 
ICQSRGIAHC ILLAKPEAVV EVAKARGIEL PDDLEIIDPD LIRNQYITPM VELRNGKLNE 

       490        500        510        520        530        540 
LQAKEQLQDT VVLGTMMLAL DQVDGLVSGA IHTTANTVRP AFQLIKTAPD YSLVSSVFFM 

       550        560        570        580        590        600 
LLPDEVYVYG DCAINPDPDA DQLAEIAIQS ADSAKAFGIN PRIAMISYST GTSGAGADVE 

       610        620        630        640        650        660 
KVAKATEIAK QRRPDLLIDG PLQYDAASVE SVGRQKAPDS QVAGRANVFI FPDLNTGNTT 

       670        680        690        700        710        720 
YKAVQRSANV VSVGPMLQGL NKPVNDLSRG ALVDDIVFTI ALTAIQAEQQ LEAKAAALAS 

« Hide

References

[1]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33305 / BD413 / ADP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR543861 Genomic DNA. Translation: CAG67466.1.
RefSeqYP_045288.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ6FEP2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING62977.ACIAD0540.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG67466; CAG67466; ACIAD0540.
GeneID2879339.
KEGGaci:ACIAD0540.
PATRIC20738982. VBIAciSp98416_0471.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OMAKPIAQPH.
OrthoDBEOG6BKJ5W.
ProtClustDBPRK05632.

Enzyme and pathway databases

BioCycASP62977:GJVV-503-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_ACIAD
AccessionPrimary (citable) accession number: Q6FEP2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: July 19, 2004
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways