Q6FEL9 (Q6FEL9_ACIAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
GTPase Der HAMAP-Rule MF_00195 RuleBase RU004481

Alternative name(s):
GTP-binding protein EngA HAMAP-Rule MF_00195

Gene names

Name:	der HAMAP-Rule MF_00195
Ordered Locus Names:	ACIAD0565

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP] EMBL CAG67489.1

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity. HAMAP-Rule MF_00195 RuleBase RU004481
Subunit structure	Associates with the 50S ribosomal subunit By similarity. HAMAP-Rule MF_00195
Sequence similarities	Belongs to the Era/MnmE GTP-binding protein family. Der subfamily. HAMAP-Rule MF_00195 RuleBase RU004481 Contains 1 KH-like domain. HAMAP-Rule MF_00195 SAAS SAAS016484 Contains 2 G (guanine nucleotide-binding) domains. HAMAP-Rule MF_00195 SAAS SAAS016484

Ontologies

Keywords
Biological process	Ribosome biogenesis HAMAP-Rule MF_00195 SAAS SAAS016484
Domain	Repeat HAMAP-Rule MF_00195 RuleBase RU004481 SAAS SAAS016484
Ligand	GTP-binding HAMAP-Rule MF_00195 SAAS SAAS016484 RuleBase RU003312 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ribosome biogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	14 – 128	115	G 1 By similarity HAMAP-Rule MF_00195
	Domain	188 – 305	118	G 2 By similarity HAMAP-Rule MF_00195
	Domain	359 – 445	87	KH-like By similarity HAMAP-Rule MF_00195
	Nucleotide binding	18 – 25	8	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	65 – 69	5	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	127 – 130	4	GTP 1 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	192 – 199	8	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	239 – 243	5	GTP 2 By similarity HAMAP-Rule MF_00195
	Nucleotide binding	304 – 307	4	GTP 2 By similarity HAMAP-Rule MF_00195

Sequences

	Sequence		Length	Mass (Da)
	Q6FEL9 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 032AF2BEB5D36887	FASTA	478	53,511
	10 20 30 40 50 60 MADLEKGYSM KPVIALIGRP NVGKSTLFNQ ITKSRDALVA DFAGLTRDRK YGDAVYQNKS 70 80 90 100 110 120 FIVVDTGGIG EGEAGIDAYM AEQSKTAIHE ADIIIFVVDA RAGLLASDEQ IAREIRSLGK 130 140 150 160 170 180 KVYLVANKVD GVHAEAAVVE FYKLGFGEPL HVAASHGRGV AQMLEDVLVD VPEDENPEDH 190 200 210 220 230 240 DKATGLRLAI IGRPNVGKST LVNRLLGEER VVAFDQPGTT RDSIYIPFER DGRQYTLIDT 250 260 270 280 290 300 AGVRRKGKVD EMIEKFSVVK TLQAMKDAHV VVVVVDAREG IVEQDLHLIG YALEAGRAMV 310 320 330 340 350 360 IAINKWDNMT EYDRKQCKLD VERRFDFIPW AKIHLISALH GTGVGELYPS IHRAYESANL 370 380 390 400 410 420 KVSPAKLTQI LNDATEAHQP PMISGRRIKM RYAHMGGQNP PTIVIHGNKV DKTPADYRRY 430 440 450 460 470 LENVFRKVYK LEGTPVRIDF KTSENPFEGR KSQVDERVAA RRRRYVQKFK KAEKKFKR

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ADP1 EMBL CAG67489.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR543861 Genomic DNA. Translation: CAG67489.1.
RefSeq	YP_045311.2. NC_005966.1.
3D structure databases
ProteinModelPortal	Q6FEL9.
ModBase	Search...
Protein-protein interaction databases
STRING	62977.ACIAD0565.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAG67489; CAG67489; ACIAD0565.
GeneID	2880990.
KEGG	aci:ACIAD0565.
PATRIC	20739028. VBIAciSp98416_0494.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1160.
HOGENOM	HOG000242862.
KO	K03977.
OMA	YLENTYR.
ProtClustDB	PRK00093.
Enzyme and pathway databases
BioCyc	ASP62977:GJVV-526-MONOMER.
Family and domain databases
Gene3D	3.30.300.20. 1 hit.
HAMAP	MF_00195. GTPase_Der.
InterPro	IPR016484. GTP-bd_EngA. IPR006073. GTP_binding_domain. IPR015946. KH_dom-like_a/b. IPR005225. Small_GTP-bd_dom. [Graphical view]
PANTHER	PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfam	PF01926. MMR_HSR1. 2 hits. [Graphical view]
PIRSF	PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTS	PR00326. GTP1OBG.
TIGRFAMs	TIGR03594. GTPase_EngA. 1 hit. TIGR00231. small_GTP. 2 hits.
ProtoNet	Search...

Entry information

Entry name

Q6FEL9_ACIAD

Accession

Primary (citable) accession number: Q6FEL9

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)