Q6FDG0 (MQO_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	ACIAD1007

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 543	543	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000023789

Sequences

	Sequence		Length	Mass (Da)
	Q6FDG0 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: F8F5A79EA4DBC168	FASTA	543	60,682
	10 20 30 40 50 60 MKKFLKYLAV FLVVLLIAAI AFLFRPIASK KIQTSANEPV VDVVLVGGGI MSATLGTYLT 70 80 90 100 110 120 ELEPNWQIRM YERLDRVAQE SSNGFNNAGT GHSGFMEMNY TEEKDGKMDI SKAVKVAEQF 130 140 150 160 170 180 EISKQFWAYQ VKHNVLGQPS SFINPVPHHA FVWGDNVAFL EKRYAAMIKN PLFYGMQFTE 190 200 210 220 230 240 NANQIKQWAP LTMEGRDPAQ KVAATRMEIG SDVNYGAITT QLVNNLDKHQ NFKLSTSSEV 250 260 270 280 290 300 TGISQNDDKT WTVAFKNLKT GKADHVKTRF VFIGAGGASV KLLQMTGLPE SKQYAGFPVG 310 320 330 340 350 360 GVFLMTDNPK IAAEHTAKLY GRAELGAPPM SVPHIDTRYI DGKKYVLFGP FATYSNKFLK 370 380 390 400 410 420 QGSQFDLLAS TNKNNVLPMT AVGMENLDLV KYLVSQVMMT DEDRFNELKK YYPNAKREDW 430 440 450 460 470 480 RLNQGGQRVQ VIKKEEGKPA KLQFGTEVFV SKDRSVTALM GASPGASTSP YIMLNLLEKA 490 500 510 520 530 540 FPQQVKGEWN PKLHEIVRSY KQDLSDNPVL LDQVRQYTSQ TLGLHYTPLT QADFAKIAAS QSK

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ADP1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR543861 Genomic DNA. Translation: CAG67898.1.
RefSeq	YP_045720.1. NC_005966.1.
3D structure databases
ProteinModelPortal	Q6FDG0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FDG0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2878499.
GenomeReviews	Gene locus ACIAD1007 in contig CR543861_GR.
KEGG	aci:ACIAD1007.
NMPDR	fig|62977.3.peg.1058.
PATRIC	20739872. VBIAciSp98416_0900.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	GKRMILF.
PhylomeDB	Q6FDG0.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD1007-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_ACIAD

Accession

Primary (citable) accession number: Q6FDG0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 19, 2004
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program