ID   Q6FCE8_ACIAD            Unreviewed;       485 AA.
AC   Q6FCE8;
DT   19-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Putative adenylate or guanylate cyclase {ECO:0000313|EMBL:CAG68263.1};
DE            EC=4.6.1.- {ECO:0000313|EMBL:CAG68263.1};
GN   OrderedLocusNames=ACIAD1397 {ECO:0000313|EMBL:CAG68263.1};
OS   Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=62977 {ECO:0000313|EMBL:CAG68263.1, ECO:0000313|Proteomes:UP000000430};
RN   [1] {ECO:0000313|EMBL:CAG68263.1, ECO:0000313|Proteomes:UP000000430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33305 / BD413 / ADP1 {ECO:0000313|Proteomes:UP000000430};
RX   PubMed=15514110; DOI=10.1093/nar/gkh910;
RA   Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA   Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA   Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT   "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT   a versatile and naturally transformation competent bacterium.";
RL   Nucleic Acids Res. 32:5766-5779(2004).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR543861; CAG68263.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6FCE8; -.
DR   STRING; 202950.GCA_001485005_01154; -.
DR   KEGG; aci:ACIAD1397; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_047397_0_0_6; -.
DR   OrthoDB; 9806704at2; -.
DR   BioCyc; ASP62977:ACIAD_RS06450-MONOMER; -.
DR   Proteomes; UP000000430; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAG68263.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000430};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        75..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        114..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          227..361
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   485 AA;  56409 MW;  6A634F92AD492FAB CRC64;
     MLTRFIERGP QQFIYFHRMM GYFILSLLIV IYSFTSAHSQ YQIYVPIFIV ILVLLIPRLN
     RVFEAKFDKK ITRSIFFLID TFVVSIVLAG VHLSLVLTFI ILFAWIYSAI NSRIPFVVMS
     LAVLSGIACF YFHTFFVFGF QGYLANTSQE LTVISLICLI IFISMGNYYQ HIYIERIKQL
     RQDYYNQMTR YMTFANQLSR YAPLQLWQSI MRGEAEAKIE YKRKKLTVFF SDIQGFTELS
     ESLIPDDLAF LLNDYLSHMT EIANQYEATI DKFMGDAILI FFGDPNSQGV QQDAASCVEM
     AIAMRQQMKL LRERWKKMGY PALNIRMGVS TGYCHVGNYG ATYRMAYTIV GRDVNLAARL
     QYAAEVDEIL ISDETYQLIK DQFLCAPKAP IYLKGIQGAV KTWQVLEKYT GNQEDLQQWF
     DYEYKGFHLL LNLEEVQRFE YSELVEVMEK MIHRIQAQQA MTNDKGIVKL SMKDEVKLAQ
     GNLKS
//