Reviewed, UniProtKB/Swiss-Prot Q6FAR2 (AROC_ACIAD)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	ACIAD2028

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Chorismate synthase HAMAP MF_00300		PRO_0000140535

Sequences

	Sequence		Length	Mass (Da)
	Q6FAR2-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: DA6219951020B7F9	FASTA	363	39,091
	10 20 30 40 50 60 MAGNSIGQLF RVTTCGESHG VGLMAIVDGV PPGLELCEED LQKDLDRRKP GTSKFATQRK 70 80 90 100 110 120 EPDQVKIISG VFEGKTTGTS IGLYIENTDQ KSKDYGNIAQ TFRPGHADYT YTQKYGFRDY 130 140 150 160 170 180 RGGGRSSARE TAMRVAAGAI AKKYLAEKFG LVVRGHVIQI GNEVAEKLDW NEVSQNPFFC 190 200 210 220 230 240 GDVDAVPRFE ALVTSLREQG TSCGAKLEIL AEQVPVGWGE PVFDRLDADI AHAMMSINAV 250 260 270 280 290 300 KGVEIGDGFA VAGQFGHETR DELSTQGFLA NHAGGILGGI SSGQTIRVAI ALKPTASITT 310 320 330 340 350 360 SGKTINLDRE DTDVLTKGRH DPCVGVRATP IAEAMLAIVL MDHFLRHRAQ NADVVMPFEP IAP

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR543861 Genomic DNA. Translation: CAG68851.1.
RefSeq	YP_046673.1.
3D structure databases
SMR	Q6FAR2. Positions 4-355.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FAR2.
Genome annotation databases
GeneID	2878788.
GenomeReviews	Gene locus ACIAD2028 in contig CR543861_GR.
KEGG	aci:ACIAD2028.
NMPDR	fig|62977.3.peg.1935.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0082.
HOGENOM	HBG292336.
OMA	SRFTTQR.
PhylomeDB	Q6FAR2.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD2028-MONOMER.
Family and domain databases
HAMAP	MF_00300_B. Chorismate_synth_B. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ACIAD

Accession

Primary (citable) accession number: Q6FAR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	July 19, 2004
Last modified:	February 9, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)