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Protein

Probable chorismate pyruvate-lyase

Gene

ubiC

Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.UniRule annotation

Catalytic activityi

Chorismate = 4-hydroxybenzoate + pyruvate.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei71SubstrateUniRule annotation1
Binding sitei110Substrate; via amide nitrogenUniRule annotation1
Binding sitei150SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable chorismate pyruvate-lyaseUniRule annotation (EC:4.1.3.40UniRule annotation)
Short name:
CLUniRule annotation
Short name:
CPLUniRule annotation
Gene namesi
Name:ubiCUniRule annotation
Ordered Locus Names:ACIAD2456
OrganismiAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Taxonomic identifieri62977 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter
Proteomesi
  • UP000000430 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002405321 – 167Probable chorismate pyruvate-lyaseAdd BLAST167

Interactioni

Protein-protein interaction databases

STRINGi62977.ACIAD2456.

Structurei

3D structure databases

ProteinModelPortaliQ6F9N7.
SMRiQ6F9N7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiC family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3161. LUCA.
HOGENOMiHOG000290112.
KOiK03181.
OMAiHAHTSWV.
OrthoDBiPOG091H047C.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6F9N7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKIQSNQIQ EQDLTPELKK WLYASGSLTQ QLTDLADGLF TVEPIQEKYQ
60 70 80 90 100
RMSFMDSRWM RMPAYHVAWV RESLLYGCEQ QPWVKAKSIF PVLSLQKKAR
110 120 130 140 150
IFKHIGKKPI GRFLFQRTTP LCERRVIRLE EGWTRQSCYT WHGCKFIVQE
160
TFLASFEQYI QHHSHSI
Length:167
Mass (Da):19,927
Last modified:July 19, 2004 - v1
Checksum:iD3B1A45E5E82E931
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR543861 Genomic DNA. Translation: CAG69227.1.
RefSeqiWP_004928440.1. NC_005966.1.

Genome annotation databases

EnsemblBacteriaiCAG69227; CAG69227; ACIAD2456.
GeneIDi25684974.
KEGGiaci:ACIAD2456.
PATRICi20742534. VBIAciSp98416_2209.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR543861 Genomic DNA. Translation: CAG69227.1.
RefSeqiWP_004928440.1. NC_005966.1.

3D structure databases

ProteinModelPortaliQ6F9N7.
SMRiQ6F9N7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi62977.ACIAD2456.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG69227; CAG69227; ACIAD2456.
GeneIDi25684974.
KEGGiaci:ACIAD2456.
PATRICi20742534. VBIAciSp98416_2209.

Phylogenomic databases

eggNOGiCOG3161. LUCA.
HOGENOMiHOG000290112.
KOiK03181.
OMAiHAHTSWV.
OrthoDBiPOG091H047C.

Enzyme and pathway databases

UniPathwayiUPA00232.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBIC_ACIAD
AccessioniPrimary (citable) accession number: Q6F9N7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 19, 2004
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.