Reviewed, UniProtKB/Swiss-Prot Q6F9C2 (RNC_ACIAD)

Names and origin

Protein names

Recommended name:
    Ribonuclease 3
    EC=3.1.26.3
Alternative name(s):
    Ribonuclease III
      Short name=RNase III

Gene names

Name:	rnc
Ordered Locus Names:	ACIAD2581

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	230 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity.
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. Contains 1 RNase III domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA processing Inferred from electronic annotation. Source: HAMAP rRNA catabolic process Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 230	230	Ribonuclease 3 HAMAP MF_00104		PRO_0000228488
Regions
	Domain	10 – 133	124	RNase III
	Domain	161 – 230	70	DRBM

Sequences

	Sequence		Length	Mass (Da)
	Q6F9C2-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 6C279B0D58BA4223	FASTA	230	26,270
	10 20 30 40 50 60 MIKTQSKLSD PRLQSRIGYE FKQLELLQLA LTHRSVSHKY NYERLEFLGD SLLGMIIANY 70 80 90 100 110 120 LYQAYPHENE GRLTRMRATL VRQEALGKIA NDLKLSRCLI LSTGELKSGG HHRESILADT 130 140 150 160 170 180 VEAIIGAIYV DSNDLNLLKN IVLKWYIPYL DHIEPTDQLK DPKSRLQEYL QARKKPLPVY 190 200 210 220 230 EVVDIQGDAP NQHFKVVCLV EGLPRVMGEG SSRRFAEQTA AAEILKLLEQ

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR543861 Genomic DNA. Translation: CAG69343.1.
RefSeq	YP_047165.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6F9C2.
Genome annotation databases
GeneID	2879534.
GenomeReviews	Gene locus ACIAD2581 in contig CR543861_GR.
KEGG	aci:ACIAD2581.
NMPDR	fig|62977.3.peg.2358.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6F9C2.
OMA	ALTHKSF.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD2581-MON.
Family and domain databases
HAMAP	MF_00104. [Tree]
InterPro	IPR001159. Ds-RNA_bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNC_ACIAD

Accession

Primary (citable) accession number: Q6F9C2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)