Reviewed, UniProtKB/Swiss-Prot Q6F982 (F16PA_ACIAD)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 1
      Short name=FBPase class 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Gene names

Name:	fbp
Ordered Locus Names:	ACIAD2625

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 323	323	Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855		PRO_0000364451
Regions
	Region	110 – 113	4	Substrate binding By similarity
Sites
	Metal binding	88	1	Magnesium 1 By similarity
	Metal binding	107	1	Magnesium 1 By similarity
	Metal binding	107	1	Magnesium 2 By similarity
	Metal binding	109	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	110	1	Magnesium 2 By similarity
	Metal binding	272	1	Magnesium 2 By similarity
	Binding site	200	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6F982-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 7D89456922E3F333	FASTA	323	35,585
	10 20 30 40 50 60 MSNLTLAQYL QQKNGNLTPE LAQVIETIAN SCKKIDHAIQ KGALADLLGS AGNENVQGET 70 80 90 100 110 120 QKKLDVLSND FLIDALKVHP HVGGLASEEL DEFTPGQQDG KYLVLFDPLD GSSNIDINMC 130 140 150 160 170 180 VGTIFSILPA KNSITQTQDF MQAGTEQVAA GYVLYGPSTM MALTCGEGVA FFTFDPESQT 190 200 210 220 230 240 FILTSDAIQL DADTQEFAIN ASNQRHWEEP VKRYIDELLA GKTSVRGKDF NMRWVACMVA 250 260 270 280 290 300 DIHRILCRSG IFMYPYDLKD PSKAGRLRLM YEANPMSFLI EQAGGSATTG RVRIMDIQPN 310 320 DLHQRVPVII GSKNEVDLVT SYH

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR543861 Genomic DNA. Translation: CAG69383.1.
RefSeq	YP_047205.1.
3D structure databases
HSSP	HSSP built from PDB template 1D9Q based on UniProtKB P46275.
SMR	Q6F982. Positions 4-323.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6F982.
Genome annotation databases
GeneID	2878536.
GenomeReviews	Gene locus ACIAD2625 in contig CR543861_GR.
KEGG	aci:ACIAD2625.
NMPDR	fig|62977.3.peg.2398.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0158.
HOGENOM	HBG731261.
OMA	QRGLMRS.
PhylomeDB	Q6F982.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD2625-MONOMER.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. Fructose_bisphosphatase. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16PA_ACIAD

Accession

Primary (citable) accession number: Q6F982

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	July 19, 2004
Last modified:	January 19, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)