Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q6F7E5 (AROB_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:ACIAD3353
OrganismAcinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3623623-dehydroquinate synthase HAMAP MF_00110
PRO_0000231060

Sequences

Sequence LengthMass (Da)Tools
Q6F7E5 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 8D97CD4034D4AB3E

FASTA36239,743
        10         20         30         40         50         60 
MQTLHVELGD RRYPIFIGSQ LNPQNLLAPY IKGRQVMIVT NTTLEQLYLQ HYQDALHALD 

        70         80         90        100        110        120 
KQVAVCVLPD GEKYKNIEHL NLIFDALLKA GFNRDCTVLA LGGGVIGDMA GFAAASFQRG 

       130        140        150        160        170        180 
VYFVQIPTTL LSQVDSSVGG KTGINHPLGK NMIGAFKQPE VVMADMSQLK TLPPRELSAG 

       190        200        210        220        230        240 
LAEVIKYALL GDIEFLGWLE THMDGLIAGD ETLLAEAVYR SCAHKARIVA NDEKEQGERA 

       250        260        270        280        290        300 
LLNLGHTFGH AIESYLGYGE WLHGEAVATG MVMAADLSHR LGWISSGDLE RTKKIIQRAN 

       310        320        330        340        350        360 
LPISCPPIPL DEFLSYMSHD KKVLNGQLRL VLLQQLGQAI ITKTFDVEMM KAAILANQAS 


HT

« Hide

References

[1]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ADP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR543861 Genomic DNA. Translation: CAG70020.1.
RefSeqYP_047842.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ6F7E5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6F7E5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2878787.
GenomeReviewsGene locus ACIAD3353 in contig CR543861_GR.
KEGGaci:ACIAD3353.
NMPDRfig|62977.3.peg.3035.
PATRIC20744165. VBIAciSp98416_2997.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ6F7E5.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycASP62977:ACIAD3353-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_ACIAD
AccessionPrimary (citable) accession number: Q6F7E5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents