Reviewed, UniProtKB/Swiss-Prot Q6F717 (GLMM_ACIAD)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	ACIAD3502

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147834
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6F717-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 164458B5CA6B3E66	FASTA	443	48,181
	10 20 30 40 50 60 MSYFGTDGIR GKFGEMPITP EFALKLGFAA GKVLKRTSPI NKPIVVLGKD TRLSGYILES 70 80 90 100 110 120 ALQAGLNAAG VYVHLLGPLP TPAIAHLTRA LHADAGIVIS ASHNPYFDNG IKFFSGEGKK 130 140 150 160 170 180 LPDSLQDEIN QELEHELHIE DTANLGKSVR LIDANGRYIE FCKSTFPYHF DLRNLTIVVD 190 200 210 220 230 240 CANGAAYNVG PSVFRELGAK VIALYNDPNG MNINEHCGST HPENLQKAVV HYKADLGIAF 250 260 270 280 290 300 DGDADRVILV DKFGELVDGD HILYILATQA KKKPAGIVGT VMSNMALELA LAKADVPFIR 310 320 330 340 350 360 AKVGDRYVLQ ALEENDWVTG GEPSGHILTL DKSTTGDAII AALQVLTVMV EQNKALHELV 370 380 390 400 410 420 TGFELFPQVL VNVRLDQMMD PYSVPALVSE FEQAEAQLKG RGRLLIRKSG TEPVIRVMVE 430 440 GDNQKEVTDL AHRLAESVRT HAA

References

[1]

"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR543861 Genomic DNA. Translation: CAG70148.1.
RefSeq	YP_047970.1.
3D structure databases
SMR	Q6F717. Positions 2-441.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6F717.
Genome annotation databases
GeneID	2881137.
GenomeReviews	Gene locus ACIAD3502 in contig CR543861_GR.
KEGG	aci:ACIAD3502.
NMPDR	fig|62977.3.peg.3163.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	STHPEAM.
PhylomeDB	Q6F717.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD3502-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACIAD

Accession

Primary (citable) accession number: Q6F717

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	July 19, 2004
Last modified:	February 9, 2010
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)