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Q6F702 (Q6F702_ACIAD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutathione synthetase HAMAP-Rule MF_00162
EC=6.3.2.3 HAMAP-Rule MF_00162
Alternative name(s):
GSH synthetase HAMAP-Rule MF_00162
Glutathione synthase HAMAP-Rule MF_00162
Gene names
Name:gshB HAMAP-Rule MF_00162 EMBL CAG70163.1
Ordered Locus Names:ACIAD3518
OrganismAcinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP] EMBL CAG70163.1
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. HAMAP-Rule MF_00162

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00162

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. HAMAP-Rule MF_00162

Sequence similarities

Belongs to the prokaryotic GSH synthase family. HAMAP-Rule MF_00162

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00162

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain123 – 309187ATP-grasp By similarity HAMAP-Rule MF_00162
Nucleotide binding150 – 20657ATP By similarity HAMAP-Rule MF_00162

Sites

Metal binding2801Magnesium or manganese By similarity HAMAP-Rule MF_00162
Metal binding2821Magnesium or manganese By similarity HAMAP-Rule MF_00162

Sequences

Sequence LengthMass (Da)Tools
Q6F702 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 67AD06369AED36EB

FASTA31435,298
        10         20         30         40         50         60 
MRVLVVMDPI ENVNLKKDST MAMLWAASRR GHELGYALQH DLYIDQGRAF GLISPLKVFE 

        70         80         90        100        110        120 
DYQHYYELGN KQKESLADYD VILMRKDPPF DMNFVYTTYI LEQAEREGAW IINKPQSLRD 

       130        140        150        160        170        180 
CNEKLFATQF PELQVPTLVT SQQSLIREFI QEHGDVIVKP LDGMGGMGIF RLYQDGVNIG 

       190        200        210        220        230        240 
STLEMLTEMG TCPIMAQRYI PEIVEGDKRI LMVNGEPIPY CLARIPQNGE VRGNLAAGGL 

       250        260        270        280        290        300 
GEARPLTEND KMIAAKVGPY LRDKGLVFVG LDVIGNYVTE INVTSPTCIR EIDAQFGTSI 

       310 
ADTLFDVLEA GRQH

« Hide

References

[1]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ADP1 EMBL CAG70163.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR543861 Genomic DNA. Translation: CAG70163.1.
RefSeqYP_047985.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ6F702.
SMRQ6F702. Positions 1-312.
ModBaseSearch...

Protein-protein interaction databases

STRING62977.ACIAD3518.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG70163; CAG70163; ACIAD3518.
GeneID2879246.
KEGGaci:ACIAD3518.
PATRIC20744469. VBIAciSp98416_3143.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0189.
HOGENOMHOG000265022.
KOK01920.
OMAWMRKDPP.
ProtClustDBPRK05246.

Enzyme and pathway databases

BioCycASP62977:GJVV-3255-MONOMER.
UniPathwayUPA00142; UER00210.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00162. GSH_S.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR006284. Glut_synth_pro.
IPR004218. GSHS_ATP-bd.
IPR004215. GSHS_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PfamPF02955. GSH-S_ATP. 1 hit.
PF02951. GSH-S_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01380. glut_syn. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6F702_ACIAD
AccessionPrimary (citable) accession number: Q6F702
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: May 1, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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