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Q6F6W1 (PNCB_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:ACIAD3562
OrganismAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205816

Sequences

Sequence LengthMass (Da)Tools
Q6F6W1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 549EAC3E9EFB05F7

FASTA40747,576
        10         20         30         40         50         60 
MLSMSPIIHS LLDTDLYKFT MLQVVLHQFP QTHSVYHFRC RNLDETQYPL TDILDDLNEQ 

        70         80         90        100        110        120 
LDHLCTLKFK DDELQYLRSF RFIKSDFVDY LELFQLKRRF ITAGIDEEGR LDIWVEGPMV 

       130        140        150        160        170        180 
QAMMFEIFVL AIVNELYFRR IRSDAVLEEG ERRLQAKLAL LEQYQTQHQS DEPPFLVSDF 

       190        200        210        220        230        240 
GTRRRYSFEW QKHVIAAFHH HFPNIFRGTS NVLLAKELNI TPIGTMAHEF LQAFQALDVR 

       250        260        270        280        290        300 
LRDFQKAALE TWVQEYRGDL GIALTDVVGM DAFLRDFDLY FAKLFDGLRH DSGDPYEWGD 

       310        320        330        340        350        360 
KAYAHYRKLK IDTKTKMLTF SDGLNLEKAW ELHQYFKGRF KVSFGIGTNL TNDMGQTPLN 

       370        380        390        400 
IVLKLVECNG QSVAKISDSP GKTMTDNDTF LAYLRQVFQI AEEEPVA 

« Hide

References

[1]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33305 / BD413 / ADP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR543861 Genomic DNA. Translation: CAG70204.1.
RefSeqYP_048026.1. NC_005966.1.

3D structure databases

ProteinModelPortalQ6F6W1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING62977.ACIAD3562.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG70204; CAG70204; ACIAD3562.
GeneID2879798.
KEGGaci:ACIAD3562.
PATRIC20744553. VBIAciSp98416_3185.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycASP62977:GJVV-3296-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_ACIAD
AccessionPrimary (citable) accession number: Q6F6W1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 19, 2004
Last modified: June 11, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways