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Q6F6W1

- PNCB_ACIAD

UniProt

Q6F6W1 - PNCB_ACIAD

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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciASP62977:GJVV-3296-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:ACIAD3562
OrganismiAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Taxonomic identifieri62977 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter
ProteomesiUP000000430: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Nicotinate phosphoribosyltransferasePRO_0000205816Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi62977.ACIAD3562.

Structurei

3D structure databases

ProteinModelPortaliQ6F6W1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6F6W1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSMSPIIHS LLDTDLYKFT MLQVVLHQFP QTHSVYHFRC RNLDETQYPL
60 70 80 90 100
TDILDDLNEQ LDHLCTLKFK DDELQYLRSF RFIKSDFVDY LELFQLKRRF
110 120 130 140 150
ITAGIDEEGR LDIWVEGPMV QAMMFEIFVL AIVNELYFRR IRSDAVLEEG
160 170 180 190 200
ERRLQAKLAL LEQYQTQHQS DEPPFLVSDF GTRRRYSFEW QKHVIAAFHH
210 220 230 240 250
HFPNIFRGTS NVLLAKELNI TPIGTMAHEF LQAFQALDVR LRDFQKAALE
260 270 280 290 300
TWVQEYRGDL GIALTDVVGM DAFLRDFDLY FAKLFDGLRH DSGDPYEWGD
310 320 330 340 350
KAYAHYRKLK IDTKTKMLTF SDGLNLEKAW ELHQYFKGRF KVSFGIGTNL
360 370 380 390 400
TNDMGQTPLN IVLKLVECNG QSVAKISDSP GKTMTDNDTF LAYLRQVFQI

AEEEPVA
Length:407
Mass (Da):47,576
Last modified:July 19, 2004 - v1
Checksum:i549EAC3E9EFB05F7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR543861 Genomic DNA. Translation: CAG70204.1.
RefSeqiWP_011182827.1. NC_005966.1.
YP_048026.1. NC_005966.1.

Genome annotation databases

EnsemblBacteriaiCAG70204; CAG70204; ACIAD3562.
GeneIDi2879798.
KEGGiaci:ACIAD3562.
PATRICi20744553. VBIAciSp98416_3185.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR543861 Genomic DNA. Translation: CAG70204.1 .
RefSeqi WP_011182827.1. NC_005966.1.
YP_048026.1. NC_005966.1.

3D structure databases

ProteinModelPortali Q6F6W1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 62977.ACIAD3562.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG70204 ; CAG70204 ; ACIAD3562 .
GeneIDi 2879798.
KEGGi aci:ACIAD3562.
PATRICi 20744553. VBIAciSp98416_3185.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci ASP62977:GJVV-3296-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
    Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
    Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33305 / BD413 / ADP1.

Entry informationi

Entry nameiPNCB_ACIAD
AccessioniPrimary (citable) accession number: Q6F6W1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 19, 2004
Last modified: October 1, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3