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Q6F5F2

- Q6F5F2_MOUSE

UniProt

Q6F5F2 - Q6F5F2_MOUSE

Protein
Submitted name:

Protein Sirpb1a

Gene

SIRP-beta

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    ReactomeiREACT_188188. DAP12 interactions.
    REACT_215628. Signal regulatory protein (SIRP) family interactions.
    REACT_225233. Cell surface interactions at the vascular wall.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Sirpb1aImported
    Submitted name:
    SIRP-beta B-typeImported
    Gene namesi
    Name:SIRP-betaImported
    Synonyms:Sirpb1aImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:2444824. Sirpb1a.

    Expressioni

    Gene expression databases

    GenevestigatoriQ6F5F2.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000096807.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00440000033339.
    HOGENOMiHOG000230874.
    HOVERGENiHBG056632.
    InParanoidiQ6F5F2.
    KOiK06551.
    OMAiKALRINI.
    OrthoDBiEOG7CG6ZQ.
    TreeFamiTF341862.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    [Graphical view]
    PfamiPF07654. C1-set. 2 hits.
    PF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00409. IG. 1 hit.
    SM00407. IGc1. 2 hits.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6F5F2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLLDAWTHI PHSVLLLILL LGFKGAAVRE LKVIQPVKSF FVGAGGSATL    50
    NCTVTSLLPV GPIRWYRGVG QSRLLIYPFT GEHSPRITNV SDVTKRNNMD 100
    FSIRISNVTP ADSGTYYCVK FQRGSSEPDI EIQSGGGTEL LVLAKPSSPM 150
    VSGPAARAVP QQTVTFTCRS HGFFPRNLTL KWFKNGDEIS HLETSVEPEE 200
    TSVSYRVSST VQVVLEPRDV RSQIICEVDH VTLDRAPLRG IAHISEFIQV 250
    PPTLEIRQQP TMVWNVINVT CQIQKFYPPS FQLTWLENGN ISRREVPFTL 300
    IVNKDGTYNW ISCLLVNISA LEENMVVTCK VEHDEQAEVI ETHTVLVTEH 350
    QRVKELKTAG IAKIPVAVLL GSKILLLIAA TVIYMHKKQN A 391
    Length:391
    Mass (Da):43,491
    Last modified:August 16, 2004 - v1
    Checksum:i56F8EBDB4CE89B7D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC152069 Genomic DNA. No translation available.
    AB112022 mRNA. Translation: BAD26608.1.
    RefSeqiNP_001002898.1. NM_001002898.1.
    UniGeneiMm.330924.
    Mm.423523.
    Mm.425126.

    Genome annotation databases

    EnsembliENSMUST00000099201; ENSMUSP00000096807; ENSMUSG00000095788.
    GeneIDi320832.
    KEGGimmu:320832.
    UCSCiuc008oqw.1. mouse.
    uc008ore.4. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC152069 Genomic DNA. No translation available.
    AB112022 mRNA. Translation: BAD26608.1 .
    RefSeqi NP_001002898.1. NM_001002898.1.
    UniGenei Mm.330924.
    Mm.423523.
    Mm.425126.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000096807.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000099201 ; ENSMUSP00000096807 ; ENSMUSG00000095788 .
    GeneIDi 320832.
    KEGGi mmu:320832.
    UCSCi uc008oqw.1. mouse.
    uc008ore.4. mouse.

    Organism-specific databases

    CTDi 320832.
    MGIi MGI:2444824. Sirpb1a.

    Phylogenomic databases

    GeneTreei ENSGT00440000033339.
    HOGENOMi HOG000230874.
    HOVERGENi HBG056632.
    InParanoidi Q6F5F2.
    KOi K06551.
    OMAi KALRINI.
    OrthoDBi EOG7CG6ZQ.
    TreeFami TF341862.

    Enzyme and pathway databases

    Reactomei REACT_188188. DAP12 interactions.
    REACT_215628. Signal regulatory protein (SIRP) family interactions.
    REACT_225233. Cell surface interactions at the vascular wall.

    Miscellaneous databases

    NextBioi 397525.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q6F5F2.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003597. Ig_C1-set.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    [Graphical view ]
    Pfami PF07654. C1-set. 2 hits.
    PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00409. IG. 1 hit.
    SM00407. IGc1. 2 hits.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Positive regulation of phagocytosis by SIRPbeta and its signaling mechanism in macrophages."
      Hayashi A., Ohnishi H., Okazawa H., Nakazawa S., Ikeda H., Motegi S., Aoki N., Kimura S., Mikuni M., Matozaki T.
      J. Biol. Chem. 279:29450-29460(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6Imported.
      Tissue: SpleenImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ6F5F2_MOUSE
    AccessioniPrimary (citable) accession number: Q6F5F2
    Secondary accession number(s): D3YXM3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 16, 2004
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3