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Q6F1L2

- G6PI_MESFL

UniProt

Q6F1L2 - G6PI_MESFL

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) (Acholeplasma florum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei276 – 2761Proton donorUniRule annotation
    Active sitei297 – 2971UniRule annotation
    Active sitei413 – 4131UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciMFLO265311:GHIB-275-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Mfl254
    OrganismiMesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) (Acholeplasma florum)
    Taxonomic identifieri265311 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesEntomoplasmatalesEntomoplasmataceaeMesoplasma
    ProteomesiUP000006647: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 426426Glucose-6-phosphate isomerasePRO_0000180671Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi265311.Mfl254.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6F1L2.
    SMRiQ6F1L2. Positions 2-425.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiAIAFREF.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6F1L2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKVDLQHSG LSIADLNEAK VKKVHEMIIN KSGKGNDFLG WIEWPKTFDK    50
    KEYEEMKKVA SSLRNKIDVL VTVGIGGSYL GIRAADEMIR GINHSDKVQV 100
    IYAGHTMSST YVAQLSEYLK GKKFGICVIS KSGTTTEPGI AFRALEKQLI 150
    EQVGVEASKE LIVAVTDSSK GALKTLADNK GYPTFVIPDD IGGRFSVLTP 200
    VGIFPLLVAG VNTDNIFAGA IKAMDELVQG DLTNEAYKYA AARNALYNAG 250
    YKAEALVAYE LQMQYTAEWW KQLFGESEGK DNKGLYPTSM IFSTDLHSLG 300
    QWVQEGARNV LFETVIKVKE PVANMLVEAD TDNYDGLNYL SGKSFHEINS 350
    TAIEGVIDAH VNTGKMPNIV LEFDKMNDVQ FGYLVYFFEI AVAMSGYLLE 400
    VNPFDQPGVE VYKYNMFKLL GKPGVK 426
    Length:426
    Mass (Da):47,034
    Last modified:August 16, 2004 - v1
    Checksum:i4E282927B6B145A6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017263 Genomic DNA. Translation: AAT75611.1.
    RefSeqiWP_011183151.1. NC_006055.1.
    YP_053495.1. NC_006055.1.

    Genome annotation databases

    EnsemblBacteriaiAAT75611; AAT75611; Mfl254.
    GeneIDi2897789.
    KEGGimfl:Mfl254.
    PATRICi22473235. VBIMesFlo3168_0254.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017263 Genomic DNA. Translation: AAT75611.1 .
    RefSeqi WP_011183151.1. NC_006055.1.
    YP_053495.1. NC_006055.1.

    3D structure databases

    ProteinModelPortali Q6F1L2.
    SMRi Q6F1L2. Positions 2-425.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 265311.Mfl254.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT75611 ; AAT75611 ; Mfl254 .
    GeneIDi 2897789.
    KEGGi mfl:Mfl254.
    PATRICi 22473235. VBIMesFlo3168_0254.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi AIAFREF.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci MFLO265311:GHIB-275-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33453 / NBRC 100688 / NCTC 11704 / L1.

    Entry informationi

    Entry nameiG6PI_MESFL
    AccessioniPrimary (citable) accession number: Q6F1L2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3