Reviewed, UniProtKB/Swiss-Prot Q6F0H8 (DEOC2_MESFL)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase 2
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase 2
      Short name=Deoxyriboaldolase 2
      Short name=DERA 2

Gene names

Name:	deoC2
Ordered Locus Names:	Mfl639

Organism

Mesoplasma florum (Acholeplasma florum) [Complete proteome] [HAMAP]

Taxonomic identifier

2151 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Entomoplasmatales › Entomoplasmataceae › Mesoplasma

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	Deoxyribose-phosphate aldolase 2 HAMAP MF_00114		PRO_0000231547
Sites
	Active site	151	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	180	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6F0H8-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: F5C51126138B7BB7	FASTA	212	23,666
	10 20 30 40 50 60 MKLNNYIDAT LLKPDATLIE INKFVDLCII KNVRCICVHI SRIAVVKEII KNTKISISGT 70 80 90 100 110 120 VSFPFGNATT KLKINEIKEC LKLGANEIDF VANIGNIKDH DWEKVNSEFQ KIRNSFKDII 130 140 150 160 170 180 IKVIFETCLL TEEEIIKCCQ IAVKNKLDFV KTSTGYSKMG ATIEHVKLMK KIVNNECKVK 190 200 210 ASGGIKTKNF ALELVEAGAE RIGTSSISEV LN

References

[1]

Birren B.W., Stange-Thomann N., Hafez N., DeCaprio D., Fisher S., Butler J., Elkins T., Kodira C.D., Major J., Wang S., Nicol R., Nusbaum C. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33453 / L1 / NBRC 100688 / NCTC 11704.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017263 Genomic DNA. Translation: AAT75995.1.
RefSeq	YP_053879.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2897734.
GenomeReviews	Gene locus Mfl639 in contig AE017263_GR.
KEGG	mfl:Mfl639.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6F0H8.
OMA	IHAIIIN.
Enzyme and pathway databases
BioCyc	MFLO265311:MFL639-MON.
BRENDA	4.1.2.4. 281333.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC2_MESFL

Accession

Primary (citable) accession number: Q6F0H8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	August 16, 2004
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)