Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6EX42 (PI5K1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 1

EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase
Diphosphoinositide kinase
PIP5K
PtdIns(4)P-5-kinase
Gene names
Name:PIPK1
Ordered Locus Names:Os03g0701800, LOC_Os03g49510
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length801 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in flowering. May suppress floral initiation by modifying the expression of genes related to floral induction. Ref.1

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Tissue specificity

Expressed in young seedlings, shoot and seeds, and at lower level in roots, stem and leaf. Ref.1

Induction

By auxin, abscisic acid, cytokinins, gibberellic acid, Ca2+, methyl jasmonate and salicylic acid. Ref.1

Miscellaneous

Transgenic plants suppressing PIPK1 show earlier heading (7 to 14 days earlier), delayed leaf development (a common phenotype observed with earlier flowering), and greater expression of floral induction genes.

Sequence similarities

Contains 8 MORN repeats.

Contains 1 PIPK domain.

Ontologies

Keywords
   Biological processDifferentiation
Flowering
   Coding sequence diversityAlternative splicing
   DomainRepeat
Signal
   LigandATP-binding
Nucleotide-binding
   Molecular functionDevelopmental protein
Kinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

flower development

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_function1-phosphatidylinositol-4-phosphate 5-kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q6EX42-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q6EX42-2)

The sequence of this isoform differs from the canonical sequence as follows:
     494-502: Missing.
Note: May be due to intron retention. No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 801780Phosphatidylinositol 4-phosphate 5-kinase 1
PRO_0000024105

Regions

Repeat41 – 6323MORN 1
Repeat64 – 8623MORN 2
Repeat87 – 10923MORN 3
Repeat110 – 13223MORN 4
Repeat133 – 15523MORN 5
Repeat156 – 17823MORN 6
Repeat182 – 20120MORN 7
Repeat202 – 22322MORN 8
Domain366 – 797432PIPK

Natural variations

Alternative sequence494 – 5029Missing in isoform 2.
VSP_015135

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified August 16, 2005. Version 2.
Checksum: A72DED14A54CDCE6

FASTA80190,680
        10         20         30         40         50         60 
MPGLHVVSFL VVLLLQLRSS GMHLVASELF WGNTLPNGDI YVGSFDGLVP HGPGKYMWTD 

        70         80         90        100        110        120 
GALYDGEWDK SKMTGRGLIQ WPSGASYEGD FRGGFIDGAG TFKGVDGSVY KGSWRMNKKH 

       130        140        150        160        170        180 
GMGTMVYSNS DTYEGFWNEG LPDEFGKYTW ADGNVYIGRW KSGKMNGSGV MQWINGDTLD 

       190        200        210        220        230        240 
CNWLNGLAHG KGYCKYASGA CYIGTWDRGL KDGHGTFYQP GSKIPCNLEV SDCLTSHDGT 

       250        260        270        280        290        300 
SASSSSNEKI TIGLLFLLQK LCKNWRLRRF LHRPRRISNG TTPVFDDNSG SHLCQDVSSK 

       310        320        330        340        350        360 
SFSADDQCLQ DSEVDKDSVY EREYVQGVLI MEQPKNEDSR MSESGIAQEN NWEKQAKGPM 

       370        380        390        400        410        420 
ETIYKGHRSY YLMLNLQLGI RYTVGKITPV PLREVRSNDF GPRARIKMYF PCEGSQYTPP 

       430        440        450        460        470        480 
HYSVDFFWKD YCPMVFRNLR EMFHIDAADY MMSICGGDSL KELSSPGKSG SIFYLSQDER 

       490        500        510        520        530        540 
FVIKTLRKTE LKIGLMKYVL QILLKMLPKY YNHVKAYDNT LITKFFGVHR ITLKPGRKVR 

       550        560        570        580        590        600 
FVVMGNMFCT ELRIHRKYDL KGSTQGRSTK KQNINENTTL KDLDLSYVFH VDKPWREALF 

       610        620        630        640        650        660 
RQIALDCMFL ESQSIIDYSM LLGIHFRAPN HLKRITSCQN ALESTGISAE TECSVALHHE 

       670        680        690        700        710        720 
ETISSKGFLL VAADEPGPAV RGSHIRGSMV RAAEGGYEEV DLVLPGTGRF RVQLGVNMPA 

       730        740        750        760        770        780 
RARKVQEDVN VEVENRDTIE EYDVVLYLGI IDILQEYNVS KRVEHAVKSL KFDPLSISAV 

       790        800 
DPNLYSRRFI SFLEKVFPEQ D 

« Hide

Isoform 2 [UniParc].

Checksum: C63D276B87126611
Show »

FASTA79289,634

References

« Hide 'large scale' references
[1]"OsPIPK 1, a rice phosphatidylinositol monophosphate kinase, regulates rice heading by modifying the expression of floral induction genes."
Ma H., Xu S.-P., Luo D., Xu Z.-H., Xue H.-W.
Plant Mol. Biol. 54:295-310(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [MRNA] OF 112-801 (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, INDUCTION.
Strain: cv. Zhonghua 11.
[2]"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species."
The rice chromosome 3 sequencing consortium
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. expand/collapse author list , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S.
Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ439082 mRNA. Translation: CAD27794.1.
AJ544688 mRNA. Translation: CAD67588.1.
AC091670 Genomic DNA. Translation: AAX95508.1.
RefSeqNP_001051005.1. NM_001057540.1.
UniGeneOs.38046.

3D structure databases

ProteinModelPortalQ6EX42.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4333833.
KEGGosa:4333833.

Organism-specific databases

GrameneQ6EX42.

Phylogenomic databases

eggNOGCOG4642.
HOGENOMHOG000193875.
KOK00889.
OMASQYTPPH.
ProtClustDBCLSN2690395.

Family and domain databases

Gene3D3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF02493. MORN. 8 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTSM00698. MORN. 8 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5K1_ORYSJ
AccessionPrimary (citable) accession number: Q6EX42
Secondary accession number(s): Q70Z13
Entry history
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: August 16, 2005
Last modified: April 16, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations