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Protein
Submitted name:

Neuronal nicotinic acetylcholine receptor, alpha5 subunit

Gene

CHRNA5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal nicotinic acetylcholine receptor, alpha5 subunitImported
Gene namesi
Name:CHRNA5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 41HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 36Neur_chan_membInterPro annotationAdd BLAST34

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
KOiK04807.

Family and domain databases

Gene3Di1.20.58.390. 1 hit.
InterProiView protein in InterPro
IPR036719. Neuro-gated_channel_TM_sf.
IPR006029. Neurotrans-gated_channel_TM.
PfamiView protein in Pfam
PF02932. Neur_chan_memb. 1 hit.
SUPFAMiSSF90112. SSF90112. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6EWN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DVREVVEDWK FIAQVLDRMF LWTFLFVSIV GSLGLFVPVI YKWANILIPV

HIGNANK
Length:57
Mass (Da):6,619
Last modified:August 16, 2004 - v1
Checksum:i36E995660FD2C213
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ584705 mRNA. Translation: CAE48367.1.
AJ584706 mRNA. Translation: CAE48368.1.
RefSeqiNP_000736.2. NM_000745.3.
NP_001294874.1. NM_001307945.1.
UniGeneiHs.1614.
Hs.719767.

Genome annotation databases

GeneIDi1138.
KEGGihsa:1138.

Similar proteinsi

Entry informationi

Entry nameiQ6EWN4_HUMAN
AccessioniPrimary (citable) accession number: Q6EWN4
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.