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Protein

MADS-box transcription factor 6

Gene

MADS6

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor. Regulates floral organ identity and floral meristem determinacy. May be involved in the control of flowering time.2 Publications

GO - Molecular functioni

  • DNA binding Source: AgBase
  • DNA binding transcription factor activity Source: InterPro
  • protein dimerization activity Source: AgBase
  • RNA polymerase II regulatory region sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • embryo sac development Source: AgBase
  • floral meristem determinacy Source: AgBase
  • floral organ development Source: AgBase
  • floral organ formation Source: AgBase
  • floral whorl morphogenesis Source: AgBase
  • floral whorl structural organization Source: AgBase
  • integument development Source: AgBase
  • meristem determinacy Source: UniProtKB
  • positive regulation of transcription, DNA-templated Source: UniProtKB
  • positive regulation of transcription by RNA polymerase II Source: InterPro
  • regulation of meristem development Source: AgBase
  • seed development Source: AgBase
  • seed growth Source: AgBase
  • specification of carpel identity Source: AgBase
  • specification of floral organ identity Source: UniProtKB
  • specification of floral organ number Source: AgBase
  • stamen formation Source: AgBase
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processDifferentiation, Flowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MADS-box transcription factor 6
Alternative name(s):
OsMADS6
Protein MOSAIC FLORAL ORGANS 1
Gene namesi
Name:MADS6
Synonyms:MFO1
Ordered Locus Names:Os02g0682200, LOC_Os02g45770
ORF Names:OJ1123_G04.6, OsJ_07942
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Abnormal and almost sterile florets. Mosaic organs and disturbed identities of palea and lodicule. Extra carpels or spikelets.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi24R → H in mfo1-1; loss of function. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002298951 – 250MADS-box transcription factor 6Add BLAST250

Proteomic databases

PaxDbiQ6EU39

Expressioni

Tissue specificityi

Expressed in the floral meristem. Highly expressed in lodicules. Expressed in palea and pistil. Weakly expressed in carpels, empty glumes and stamens. Not detected in lemmas.2 Publications

Developmental stagei

Expressed during ovule development in the inner and outer integuments. Not detected in young panicles.2 Publications

Gene expression databases

ExpressionAtlasiQ6EU39 differential
GenevisibleiQ6EU39 OS

Interactioni

Subunit structurei

May interact with the K-box of MADS1, MADS5, MADS7, MADS8, MADS14, MADS15, MADS16, MADS17 and MADS18. May interact with MADS13. The dimer composed of MADS6 and MADS18 forms a ternary complex with histone fold protein NF-YB1.

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein dimerization activity Source: AgBase

Protein-protein interaction databases

IntActiQ6EU39, 15 interactors
STRINGi39947.LOC_Os02g45770.1

Structurei

3D structure databases

ProteinModelPortaliQ6EU39
SMRiQ6EU39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxPROSITE-ProRule annotationAdd BLAST61
Domaini86 – 176K-boxPROSITE-ProRule annotationAdd BLAST91

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
HOGENOMiHOG000155301
InParanoidiQ6EU39
KOiK09264
OMAiRKERHLG
OrthoDBiEOG09360JNU

Family and domain databases

CDDicd00265 MADS_MEF2_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033896 MADS_MEF2-like
IPR002487 TF_Kbox
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF01486 K-box, 1 hit
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS51297 K_BOX, 1 hit
PS00350 MADS_BOX_1, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6EU39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRGRVELKR IENKINRQVT FSKRRNGLLK KAYELSVLCD AEVALIIFSS
60 70 80 90 100
RGKLYEFGSA GITKTLERYQ HCCYNAQDSN NALSETQSWY HEMSKLKAKF
110 120 130 140 150
EALQRTQRHL LGEDLGPLSV KELQQLEKQL ECALSQARQR KTQLMMEQVE
160 170 180 190 200
ELRRKERQLG EINRQLKHKL EVEGSTSNYR AMQQASWAQG AVVENGAAYV
210 220 230 240 250
QPPPHSAAMD SEPTLQIGYP HQFVPAEANT IQRSTAPAGA ENNFMLGWVL
Length:250
Mass (Da):28,437
Last modified:August 16, 2004 - v1
Checksum:i7E574BD86A48220C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78782 mRNA Translation: AAB64250.1
FJ666318 mRNA Translation: ACV89861.1
AP004178 Genomic DNA Translation: BAD27830.1
AP008208 Genomic DNA Translation: BAF09663.1
AP014958 Genomic DNA Translation: BAS80308.1
CM000139 Genomic DNA Translation: EEE57586.1
AK069103 mRNA Translation: BAG91254.1
PIRiT04167
RefSeqiXP_015623947.1, XM_015768461.1
UniGeneiOs.7271

Genome annotation databases

EnsemblPlantsiOs02t0682200-01; Os02t0682200-01; Os02g0682200
GeneIDi4330328
GrameneiOs02t0682200-01; Os02t0682200-01; Os02g0682200
KEGGiosa:4330328

Similar proteinsi

Entry informationi

Entry nameiMADS6_ORYSJ
AccessioniPrimary (citable) accession number: Q6EU39
Secondary accession number(s): A0A0P0VN09, O24228, Q0DYM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: August 16, 2004
Last modified: May 23, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations

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