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Q6EU10 (MTA70_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable N6-adenosine-methyltransferase MT-A70-like

EC=2.1.1.62
Gene names
Ordered Locus Names:Os02g0672600, LOC_Os02g45110
ORF Names:OJ1197_E09.7, OJ1493_H11.20
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length706 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation By similarity.

Catalytic activity

S-adenosyl-L-methionine + m7G(5')pppAm = S-adenosyl-L-homocysteine + m7G(5')pppm6Am.

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the MT-A70-like family.

Ontologies

Keywords
   Cellular componentNucleus
   LigandRNA-binding
S-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentchloroplast

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

nuclear speck

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 706706Probable N6-adenosine-methyltransferase MT-A70-like
PRO_0000260072

Regions

Compositional bias252 – 2576Poly-Gln

Experimental info

Sequence conflict5041M → I in AK101174. Ref.3
Sequence conflict5131D → N in AK101174. Ref.3
Sequence conflict5371R → L in AK070286. Ref.3
Sequence conflict6141K → R in AK101174. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q6EU10 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 91BDDF2AAEABA405

FASTA70677,803
        10         20         30         40         50         60 
MEAQADAGGD DLAAMREQCR SLEEAIGFRR ETQMGLVASL QRLVPDLVPS LDRSLRIIAA 

        70         80         90        100        110        120 
FNDRPFVPTP NPDGGHGKSP AALKPHHRRA LPDPARSTRR KTSPGSSPAS VAAAPGGLDA 

       130        140        150        160        170        180 
VRTMVAVCLL ELVPFAEIDA AALARRLQAE SSSASEAERT ALADLAAELG GSAASAVVLA 

       190        200        210        220        230        240 
LRRIAEDTGG VQIEEAMIGG KSMTMVWAID RNKLLKELPE SATLPLLQPP PAPQMPPSET 

       250        260        270        280        290        300 
DAGSAMIPRT PQQQQPQPDM WPHSMPPIFP RPRGMTMQGM QRVPGVPPGL MPLQRPFMGP 

       310        320        330        340        350        360 
AGVITMGGGV GPSPNQQKQK SEEDELKDLE LLLNKKTYRE KQNTKTGEEL LDLIHRPTAK 

       370        380        390        400        410        420 
ETAVAAKFKT KGGSQLKEYC TNLTKEDCRR QSGSFVACDK VHFRRIIAPH TDTNLGDCSF 

       430        440        450        460        470        480 
LDTCRHTKTC KYVHYELDQT PDIPPMMAGA LAPPRQIRLQ RAEYCSEVEL GEAQWINCDI 

       490        500        510        520        530        540 
RNFRMDILGQ FGVIMADPPW DIHMELPYGT MADDEMRTLN VPALQTDGLI FLWVTGRAME 

       550        560        570        580        590        600 
LGRECLELWG YKRVEEIIWV KTNQLQRIIR TGRTGHWLNH SKEHCLVGIK GNPLVNRNID 

       610        620        630        640        650        660 
TDVIVAEVRE TSRKPDEMYP MLERISPRTR KLELFARMHN AHAGWLSLGN QLNGVRLVDE 

       670        680        690        700 
GLRARYKAAY PDSEVQPPSP PRASAPIDGD QGTSQKPTVS DGERPA 

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP004160 Genomic DNA. Translation: BAD27818.1.
AP004188 Genomic DNA. Translation: BAD27860.1.
AP008208 Genomic DNA. Translation: BAF09621.1.
AK070286 mRNA. No translation available.
AK101174 mRNA. No translation available.
RefSeqNP_001047707.1. NM_001054242.1.
UniGeneOs.20898.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING39947.LOC_Os02g45110.1.

Proteomic databases

PRIDEQ6EU10.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS02T0672600-01; OS02T0672600-01; OS02G0672600.
GeneID4330284.
KEGGosa:4330284.

Organism-specific databases

GrameneQ6EU10.

Phylogenomic databases

eggNOGCOG4725.
HOGENOMHOG000077476.
KOK05925.
OMAELFARMH.
ProtClustDBCLSN2686057.

Family and domain databases

InterProIPR007757. MT-A70-like.
[Graphical view]
PfamPF05063. MT-A70. 1 hit.
[Graphical view]
PROSITEPS51143. MT_A70. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTA70_ORYSJ
AccessionPrimary (citable) accession number: Q6EU10
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: August 16, 2004
Last modified: March 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations