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Q6EHZ3

- Q6EHZ3_HUMAN

UniProt

Q6EHZ3 - Q6EHZ3_HUMAN

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Protein
Submitted name: Putative uncharacterized protein STRF8
Gene
STRF8
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. isomerase activity Source: InterPro

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein STRF8Imported
Gene namesi
Name:STRF8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: Ensembl
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiQ6EHZ3.

Expressioni

Gene expression databases

BgeeiQ6EHZ3.

Structurei

3D structure databases

ProteinModelPortaliQ6EHZ3.
SMRiQ6EHZ3. Positions 253-363.

Family & Domainsi

Sequence similaritiesi

Contains 3 thioredoxin domains.UniRule annotation

Keywords - Domaini

Redox-active centerSAAS annotations, RepeatSAAS annotations

Phylogenomic databases

HOVERGENiHBG058611.
KOiK13984.

Family and domain databases

Gene3Di3.40.30.10. 3 hits.
InterProiIPR005788. Disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 3 hits.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 3 hits.
TIGRFAMsiTIGR01126. pdi_dom. 1 hit.
PROSITEiPS00194. THIOREDOXIN_1. 3 hits.
PS51352. THIOREDOXIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6EHZ3-1 [UniParc]FASTAAdd to Basket

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MFTHGIQSAA HFVMFFAPWC GHCQRLQPTW NDLGDKYNSM EDAKVYVAKV    50
DCTAHSDVCS AQGVRGYPTL KLFKPGQEAV KYQGPRDFQT LENWMLQTLN 100
EEPVTPEPEV EPPSAPELKQ GLYELSASNF ELHVAQGDHF IKFFAPWCGH 150
CKALAPTWEQ LALGLEHSET VKIGKVDCTQ HYELCSGNQV RGYPTLLWFR 200
DGKKVDQYKG KRDLESLREY VESQLQRTET GATETVTPSE APVLAAEPEA 250
DKGTVLALTE NNFDDTIAEG ITFIKFYAPW CGHCKTLAPT WEELSKKEFP 300
GLAGVKIAEV DCTAERNICS KYSVRGYPTL LLFRGGKKVS EHSGGRDLDS 350
LHRFVLSQAK DEL 363
Length:363
Mass (Da):40,703
Last modified:May 10, 2005 - v1
Checksum:i69FA8AFC43768973
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY326464 mRNA. Translation: AAR99514.1.
RefSeqiNP_001139021.1. NM_001145549.2.
NP_110437.2. NM_030810.3.
UniGeneiHs.150837.

Genome annotation databases

GeneIDi81567.
KEGGihsa:81567.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY326464 mRNA. Translation: AAR99514.1 .
RefSeqi NP_001139021.1. NM_001145549.2.
NP_110437.2. NM_030810.3.
UniGenei Hs.150837.

3D structure databases

ProteinModelPortali Q6EHZ3.
SMRi Q6EHZ3. Positions 253-363.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6EHZ3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 81567.
KEGGi hsa:81567.

Organism-specific databases

CTDi 81567.

Phylogenomic databases

HOVERGENi HBG058611.
KOi K13984.

Miscellaneous databases

GenomeRNAii 81567.
NextBioi 71856.

Gene expression databases

Bgeei Q6EHZ3.

Family and domain databases

Gene3Di 3.40.30.10. 3 hits.
InterProi IPR005788. Disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view ]
Pfami PF00085. Thioredoxin. 3 hits.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 3 hits.
TIGRFAMsi TIGR01126. pdi_dom. 1 hit.
PROSITEi PS00194. THIOREDOXIN_1. 3 hits.
PS51352. THIOREDOXIN_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and Identification of Novel Genes Related with IL-6 induction."
    Huang Y., Shi B., Chen Y., Shen B., Chen R.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6EHZ3_HUMAN
AccessioniPrimary (citable) accession number: Q6EHZ3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 3, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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