Q6EHZ3 (Q6EHZ3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein STRF8 EMBL AAR99514.1

Gene names

Name:

STRF8 EMBL AAR99514.1

Organism

Homo sapiens (Human) EMBL AAR99514.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the protein disulfide isomerase family. RuleBase RU004208 Contains 3 thioredoxin domains. RuleBase RU004207

Ontologies

Keywords
Domain	Redox-active center SAAS SAAS005746 Repeat SAAS SAAS005746
PTM	Disulfide bond SAAS SAAS005746
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro glycerol ether metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	endoplasmic reticulum lumen Inferred from electronic annotation. Source: Compara
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro isomerase activity Inferred from electronic annotation. Source: InterPro protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6EHZ3 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 69FA8AFC43768973	FASTA	363	40,703
	10 20 30 40 50 60 MFTHGIQSAA HFVMFFAPWC GHCQRLQPTW NDLGDKYNSM EDAKVYVAKV DCTAHSDVCS 70 80 90 100 110 120 AQGVRGYPTL KLFKPGQEAV KYQGPRDFQT LENWMLQTLN EEPVTPEPEV EPPSAPELKQ 130 140 150 160 170 180 GLYELSASNF ELHVAQGDHF IKFFAPWCGH CKALAPTWEQ LALGLEHSET VKIGKVDCTQ 190 200 210 220 230 240 HYELCSGNQV RGYPTLLWFR DGKKVDQYKG KRDLESLREY VESQLQRTET GATETVTPSE 250 260 270 280 290 300 APVLAAEPEA DKGTVLALTE NNFDDTIAEG ITFIKFYAPW CGHCKTLAPT WEELSKKEFP 310 320 330 340 350 360 GLAGVKIAEV DCTAERNICS KYSVRGYPTL LLFRGGKKVS EHSGGRDLDS LHRFVLSQAK DEL

References

[1]	"Cloning and Identification of Novel Genes Related with IL-6 induction." Huang Y., Shi B., Chen Y., Shen B., Chen R. Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY326464 mRNA. Translation: AAR99514.1.
IPI	IPI00171438.
RefSeq	NP_001139021.1. NM_001145549.2. NP_110437.2. NM_030810.3.
UniGene	Hs.150837.
3D structure databases
ProteinModelPortal	Q6EHZ3.
SMR	Q6EHZ3. Positions 253-363.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6EHZ3.
Proteomic databases
PRIDE	Q6EHZ3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	81567.
KEGG	hsa:81567.
Organism-specific databases
CTD	81567.
Phylogenomic databases
HOVERGEN	HBG058611.
KO	K13984.
Gene expression databases
ArrayExpress	Q6EHZ3.
Bgee	Q6EHZ3.
Family and domain databases
Gene3D	3.40.30.10. 3 hits.
InterPro	IPR005788. Disulphide_isomerase. IPR005746. Thioredoxin. IPR012336. Thioredoxin-like_fold. IPR017937. Thioredoxin_CS. IPR013766. Thioredoxin_domain. [Graphical view]
Pfam	PF00085. Thioredoxin. 3 hits. [Graphical view]
PRINTS	PR00421. THIOREDOXIN.
SUPFAM	SSF52833. Thiordxn-like_fd. 3 hits.
TIGRFAMs	TIGR01126. pdi_dom. 1 hit.
PROSITE	PS00194. THIOREDOXIN_1. 3 hits. PS51352. THIOREDOXIN_2. 3 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	81567.
NextBio	71856.

Entry information

Entry name

Q6EHZ3_HUMAN

Accession

Primary (citable) accession number: Q6EHZ3

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	March 6, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.