ID   ATG9B_MOUSE             Reviewed;         922 AA.
AC   Q6EBV9; Q674R6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   19-JAN-2010, entry version 42.
DE   RecName: Full=Autophagy-related protein 9B;
DE   AltName: Full=APG9-like 2;
DE   AltName: Full=Nitric oxide synthase 3-overlapping antisense gene protein;
GN   Name=Atg9b; Synonyms=Apg9l2, Nos3as;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=129S6/SvEvTac, and CD-1; TISSUE=Placenta;
RX   PubMed=15234981; DOI=10.1074/jbc.M400271200;
RA   Robb G.B., Carson A.R., Tai S.C., Fish J.E., Singh S., Yamada T.,
RA   Scherer S.W., Nakabayashi K., Marsden P.A.;
RT   "Post-transcriptional regulation of endothelial nitric-oxide synthase
RT   by an overlapping antisense mRNA transcript.";
RL   J. Biol. Chem. 279:37982-37996(2004).
RN   [2]
RP   FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX   PubMed=15755735; DOI=10.1074/jbc.M413957200;
RA   Yamada T., Carson A.R., Caniggia I., Umebayashi K., Yoshimori T.,
RA   Nakabayashi K., Scherer S.W.;
RT   "Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an
RT   autophagy-related protein (APG9-like2) highly expressed in
RT   trophoblast.";
RL   J. Biol. Chem. 280:18283-18290(2005).
CC   -!- FUNCTION: Plays a role in autophagy.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome membrane;
CC       Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Expressed in heart, brain, and placenta and
CC       testis.
CC   -!- SIMILARITY: Belongs to the ATG9 family.
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DR   EMBL; AY495541; AAS72555.1; -; mRNA.
DR   EMBL; AY515312; AAS87213.1; ALT_INIT; mRNA.
DR   EMBL; AY515313; AAS87214.1; -; mRNA.
DR   EMBL; BK004021; DAA05202.1; -; mRNA.
DR   IPI; IPI00268141; -.
DR   RefSeq; NP_001002897.2; -.
DR   UniGene; Mm.332252; -.
DR   STRING; Q6EBV9; -.
DR   PRIDE; Q6EBV9; -.
DR   Ensembl; ENSMUST00000059401; ENSMUSP00000051864; ENSMUSG00000038295; Mus musculus.
DR   GeneID; 213948; -.
DR   KEGG; mmu:213948; -.
DR   UCSC; uc008wrf.1; mouse.
DR   CTD; 213948; -.
DR   MGI; MGI:2685420; Atg9b.
DR   eggNOG; roNOG06068; -.
DR   HOGENOM; HBG315812; -.
DR   HOVERGEN; Q6EBV9; -.
DR   InParanoid; Q6EBV9; -.
DR   PhylomeDB; Q6EBV9; -.
DR   NextBio; 374136; -.
DR   ArrayExpress; Q6EBV9; -.
DR   Bgee; Q6EBV9; -.
DR   Genevestigator; Q6EBV9; -.
DR   GO; GO:0005776; C:autophagic vacuole; IDA:MGI.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007241; Autophagy-rel_prot_9.
DR   PANTHER; PTHR13038; APG9; 1.
DR   Pfam; PF04109; APG9; 1.
PE   2: Evidence at transcript level;
KW   Autophagy; Cytoplasmic vesicle; Membrane; Transmembrane.
FT   CHAIN         1    922       Autophagy-related protein 9B.
FT                                /FTId=PRO_0000314868.
FT   TOPO_DOM      1    206       Cytoplasmic (By similarity).
FT   TRANSMEM    207    227       Potential.
FT   TOPO_DOM    228    275       Lumenal (By similarity).
FT   TRANSMEM    276    296       Potential.
FT   TOPO_DOM    297    437       Cytoplasmic (By similarity).
FT   TRANSMEM    438    458       Potential.
FT   TOPO_DOM    459    523       Lumenal (By similarity).
FT   TRANSMEM    524    544       Potential.
FT   TOPO_DOM    545    550       Cytoplasmic (By similarity).
FT   TRANSMEM    551    571       Potential.
FT   TOPO_DOM    572    624       Lumenal (By similarity).
FT   TRANSMEM    625    645       Potential.
FT   TOPO_DOM    646    922       Cytoplasmic (By similarity).
FT   COMPBIAS     86    146       Pro-rich.
SQ   SEQUENCE   922 AA;  101953 MW;  450179EDD6C8496A CRC64;
     MVRRTGWGGS RRQRGRWGDL GPSSVPLLHM ALPLPASPCR GTGGRRISVF SLSPAPRTRS
     CSSSVFPPAS GSPCLVIQEA GASQTPHNVL PTPTTPSTQA HPTMIHTSAS PSWGSHSTPP
     LASATPPPSC PRPQDHPGLR MGPLIPEQDY ERLEDCDPEG SQDSPIHGED HQPLLHVPEG
     LRGSWHHIQN LDSFFTKIYS YHQRNGFACI LLEDVFQLGQ FIFIVTFTTF LLRCVDYNVL
     FNNQPKNHTR RGPLHSKVTL SDAILPSAQC AEKIHDSPLL VFLLVLAAGF WLFQLLRSVC
     NLFSYWDIQV FYREALHIPP EELSSVPWAE VQSRLLELQR SGGLCVQPRP LTELDVHHRI
     LRYTNYQVAL ANKGLLPARC PLPWGSSAAF LSRGLALNVD LLLFRGPFSL FRGGWELPEA
     YKRSDLRGVL ANRWRRTVLL LAAVNLALSP LVLAWQVLHA FYSHVELLRR EPGAFGARRW
     SRLARLQLRH FNELPHELRA RLGRAYRPAA AFLRAAEPPA PLRALLARQL VFFSGALFAA
     LLVLTIYDED VLAVEHVLTT MTALGVTATV ARSFIPEEQC QGRSSQLLLQ AALAHMHYLP
     EEPGATGARA SSYWQMAQLL QYRAVSLLEE LLSPLLTPLF LLFWFRPRAL EIIDFFHHFT
     VDVAGVGDIC SFALMDVKRH GHPQWLSEGQ TEASLSQRAE DGKTELSLMR FSLAHPQWQP
     PGHSSKFLGH LRGRVQQDAA AWGAPSTRSP PTPGVLSDCT SPLPEAFLAN LLVNPRPPQR
     DLSPTAPCPA AATASLLASI SRMVQDPSCV SPGGTGGQKL TQLPELVSAE MSLHAIYLHQ
     LHQQQQQELW GEASASSPSR PWSSPSQPGS PDEEKPSWSS DGSSPASSPR QQWGTQRAQN
     LFPKGFQENT DTQKEPLTGP LH
//