Q6E0B2 (Q6E0B2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Small intestine SPAK-like kinase EMBL AAT65492.1
Organism	Homo sapiens (Human) EMBL AAT65492.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	476 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase EMBL AAT65492.1 Transferase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6E0B2 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 80BE4779EEAD5649	FASTA	476	52,627
	10 20 30 40 50 60 MAEPSGSPVH VQLPQQAAPI GSGATAVVQA ALCKPRQERV AIKRINLEKC QTSMDELLKE 70 80 90 100 110 120 IQAMSQCSHP NVVTYYTSFV VKDELWLVMK LLSGGSMLDI IKYIVNRGEH KNGVLEEAII 130 140 150 160 170 180 ATILKEVLEG LDYLHRNGQI HRDLKAGNIL LGEDGSVQIA DFGVSAFLAT GGDVTRNKVR 190 200 210 220 230 240 KTFVGTPCWM APEVMELATG AAPYHKYPPM KVLMLTLQND PPTLETGVED KEMMKKYGKS 250 260 270 280 290 300 FRKLLSLCLQ KDPSKRPTAA ELLKCKFFQK AKNREYLIEK LLTRTPDIAQ RAKKVRRVPG 310 320 330 340 350 360 SSGHLHKTED GDWEWSDDEM DEKSEEGKAA FSQEKSRRVK EENPEIAVSA STIPEQIQSL 370 380 390 400 410 420 SVHDSQGPPN ANEDYREASS CAVNLVLRLR NSRKELNDIR FEFTPGRDTA DGVSQELFSA 430 440 450 460 470 GLVDGHDVVI VAANLQKIVD DPKALKTLTF KLASGCDGSE IPDEVKLIGF AQLSVS

References

[1]	"Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform." Yan Y., Nguyen H., Dalmasso G., Sitaraman S.V., Merlin D. Biochim. Biophys. Acta 1769:106-116(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY629298 mRNA. Translation: AAT65492.1.
IPI	IPI00973560.
3D structure databases
ProteinModelPortal	Q6E0B2.
SMR	Q6E0B2. Positions 20-275, 383-476.
ModBase	Search...
Proteomic databases
PRIDE	Q6E0B2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG108518.
Enzyme and pathway databases
BRENDA	2.7.11.1. 247.
SignaLink	Q6E0B2.
Gene expression databases
ArrayExpress	Q6E0B2.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR024678. Kinase_OSR1/WNK_CCT. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. [Graphical view]
Pfam	PF12202. OSR1_C. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6E0B2_HUMAN

Accession

Primary (citable) accession number: Q6E0B2

Entry history

Integrated into UniProtKB/TrEMBL:	August 16, 2004
Last sequence update:	August 16, 2004
Last modified:	May 29, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.