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Protein
Submitted name:

HLA-G histocompatibility antigen, class I, G, isoform CRA_a

Gene

HLA-G

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Submitted name:
HLA-G histocompatibility antigen, class I, G, isoform CRA_aImported
Submitted name:
MHC class Ib antigenImported
Submitted name:
Truncated MHC class I antigenImported
Gene namesi
Name:HLA-GImported
ORF Names:hCG_1999524Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000204632.11

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei308 – 332HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35083

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501458728025 – 338Sequence analysisAdd BLAST314

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ6DU14

Expressioni

Gene expression databases

BgeeiENSG00000204632

Structurei

3D structure databases

SMRiQ6DU14
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 287Ig-likeInterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410II5V Eukaryota
ENOG4111K8F LUCA
HOVERGENiHBG016709
KOiK06751

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DU14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVMAPRTLF LLLSGALTLT ETWAGSHSMR YFSAAVSRPG RGEPRFIAMG
60 70 80 90 100
YVDDTQFVRF DSDSACPRME PRAPWVEQEG PEYWEEETRN TKAHAQTDRM
110 120 130 140 150
NLQTLRGYYN QSEASSHTLQ WMIGCDLGSD GRLLRGYEQY AYDGKDYLAL
160 170 180 190 200
NEDLRSWTAA DTAAQISKRK CEAANVAEQR RAYLEGTCVE WLHRYLENGK
210 220 230 240 250
EMLQRADPPK THVTHHPVFD YEATLRCWAL GFYPAEIILT WQRDGEDQTQ
260 270 280 290 300
DVELVETRPA GDGTFQKWAA VVVPSGEEQR YTCHVQHEGL PEPLMLRWKQ
310 320 330
SSLPTIPIMG IVAGLVVLAA VVTGAAVAAV LWRKKSSD
Length:338
Mass (Da):38,224
Last modified:May 10, 2005 - v1
Checksum:i0678E263BE8962FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF523298 Genomic DNA Translation: AAM74993.1
AF523300 Genomic DNA Translation: AAM74994.1
AF523301 Genomic DNA Translation: AAM74995.1
AF523302 Genomic DNA Translation: AAM74996.1
AF523305 Genomic DNA Translation: AAM74999.1
AF523306 Genomic DNA Translation: AAM75000.1
AF523309 Genomic DNA Translation: AAM75003.1
AY645760 Genomic DNA Translation: AAT73243.1
AY645761 Genomic DNA Translation: AAT73244.1
AY645762 Genomic DNA Translation: AAT73245.1
AY645763 Genomic DNA Translation: AAT73246.1
AY645764 Genomic DNA Translation: AAT73247.1
AY645765 Genomic DNA Translation: AAT73248.1
AY645766 Genomic DNA Translation: AAT73249.1
AY645768 Genomic DNA Translation: AAT73251.1
AY645769 Genomic DNA Translation: AAT73252.1
AY645770 Genomic DNA Translation: AAT73253.1
AY645771 Genomic DNA Translation: AAT73254.1
AY645774 Genomic DNA Translation: AAT73257.1
AY645775 Genomic DNA Translation: AAT73258.1
AY645776 Genomic DNA Translation: AAT73259.1
FJ805838 Genomic DNA Translation: ACZ37195.1
FJ805839 Genomic DNA Translation: ACZ37196.1
GU324263 Genomic DNA Translation: ADB85517.1
GQ996557 Genomic DNA Translation: ADN34672.1
GQ996563 Genomic DNA Translation: ADN34678.1
GQ996565 Genomic DNA Translation: ADN34680.1
GQ996566 Genomic DNA Translation: ADN34681.1
GQ996568 Genomic DNA Translation: ADN34683.1
GQ996569 Genomic DNA Translation: ADN34684.1
GU070582 Genomic DNA Translation: ADP21921.1
GU370776 Genomic DNA Translation: ADQ89756.1
HQ441165 Genomic DNA Translation: AEQ39730.1
JQ013008 Genomic DNA Translation: AEZ53223.1
JQ013009 Genomic DNA Translation: AEZ53224.1
MF538779 Genomic DNA Translation: ATE50884.1
MF538780 Genomic DNA Translation: ATE50885.1
KY440187 Genomic DNA Translation: ATZ76001.1
MG825347 Genomic DNA Translation: AUW30180.1
MG825351 Genomic DNA Translation: AUW30184.1
MG825352 Genomic DNA Translation: AUW30185.1
MG825353 Genomic DNA Translation: AUW30186.1
MG825355 Genomic DNA Translation: AUW30188.1
MG825356 Genomic DNA Translation: AUW30189.1
MG825358 Genomic DNA Translation: AUW30191.1
MG825359 Genomic DNA Translation: AUW30192.1
MG825362 Genomic DNA Translation: AUW30195.1
MG825363 Genomic DNA Translation: AUW30196.1
MG825364 Genomic DNA Translation: AUW30197.1
MG825365 Genomic DNA Translation: AUW30198.1
CH471081 Genomic DNA Translation: EAX03231.1
CH471081 Genomic DNA Translation: EAX03234.1
CH471081 Genomic DNA Translation: EAX03235.1
RefSeqiNP_002118.1, NM_002127.5
UniGeneiHs.512152

Genome annotation databases

GeneIDi3135
KEGGihsa:3135
UCSCiuc003nnw.2 human

Similar proteinsi

Entry informationi

Entry nameiQ6DU14_HUMAN
AccessioniPrimary (citable) accession number: Q6DU14
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 20, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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