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Protein

Protein S-acyltransferase 21

Gene

PAT21

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

S-acyltransferase involved in protein lipid modification.2 Publications

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei174S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.225. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein S-acyltransferase 21 (EC:2.3.1.225)
Alternative name(s):
Probable palmitoyltransferase At2g33640
Zinc finger DHHC domain-containing protein At2g33640
Gene namesi
Name:PAT21
Ordered Locus Names:At2g33640
ORF Names:F4P9.41
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRilocus:2051068. AT2G33640.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalSequence analysisAdd BLAST21
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Transmembranei192 – 212HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003635911 – 565Protein S-acyltransferase 21Add BLAST565

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ6DR03.
PRIDEiQ6DR03.

PTM databases

iPTMnetiQ6DR03.

Expressioni

Gene expression databases

ExpressionAtlasiQ6DR03. baseline and differential.
GenevisibleiQ6DR03. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G33640.1.

Structurei

3D structure databases

ProteinModelPortaliQ6DR03.
SMRiQ6DR03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini144 – 194DHHCPROSITE-ProRule annotationAdd BLAST51

Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
HOGENOMiHOG000242421.
InParanoidiQ6DR03.
KOiK20027.
OMAiYVAISVY.
OrthoDBiEOG093606N7.
PhylomeDBiQ6DR03.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
PROSITEiView protein in PROSITE
PS50216. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DR03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRHGWQLP AHTFQVVAIT VFFLLTVAYY AFFAPFLGNK LYEYIAIGVY
60 70 80 90 100
SFLAFSVLVL YIRCTGIDPA DPGIFVKADN TPAHKSQNSN YVPENASAID
110 120 130 140 150
GGPYIRHGSG CCSAIGRFIC GCLVIQDCRR DTQQEQSNEQ EEALFCSLCN
160 170 180 190 200
AEVRMFSKHC RSCGKCVDGF DHHCRWLNNC VGQKNYISFV CLMAASFFWL
210 220 230 240 250
IAEFGVGVTV FVRCFVDQKA MEHLITEKLG LGFSRPPFAA VVVVCTTLSL
260 270 280 290 300
LALIPLGELF FFHMILIRKG ITTYEYVVAL RAQTEPLGTS VDELDQTSQY
310 320 330 340 350
PSPASSAVTA TSARSSLGLS IQYRGASLCT PPNIFVDQQD DVIQHLEPGP
360 370 380 390 400
VRSTIDPDSL SQKKPPQRQQ VRINPWKLAK LDSKEASKAA AKARASSSVL
410 420 430 440 450
LPVSSRQNPY KTSSNVSGRS SPGRGKPADS ESCSLSSPGL TRDHFNPMYM
460 470 480 490 500
SSPANESPLN EEESRNAVVA ARRNLPSSDE SSVVWDPEAG RFVSLSRIPG
510 520 530 540 550
TDVGGPLGNE CLNTITSTGT DRSRRARGNP LTGYFQQVRS QRGDQLPVFM
560
PTDSQLHRHL STRFH
Length:565
Mass (Da):62,139
Last modified:August 16, 2004 - v1
Checksum:iB5AA41AD7BA8F821
GO

Sequence cautioni

The sequence AAB80679 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti264M → T (PubMed:12481096).Curated1
Sequence conflicti264M → T in AAM76752 (PubMed:16244158).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002332 Genomic DNA. Translation: AAB80679.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC08865.1.
AY102547 mRNA. Translation: AAM76752.1.
AY649312 mRNA. Translation: AAT69229.1.
PIRiA84748.
RefSeqiNP_180922.2. NM_128924.4.
UniGeneiAt.37901.

Genome annotation databases

EnsemblPlantsiAT2G33640.1; AT2G33640.1; AT2G33640.
GeneIDi817930.
GrameneiAT2G33640.1; AT2G33640.1; AT2G33640.
KEGGiath:AT2G33640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002332 Genomic DNA. Translation: AAB80679.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC08865.1.
AY102547 mRNA. Translation: AAM76752.1.
AY649312 mRNA. Translation: AAT69229.1.
PIRiA84748.
RefSeqiNP_180922.2. NM_128924.4.
UniGeneiAt.37901.

3D structure databases

ProteinModelPortaliQ6DR03.
SMRiQ6DR03.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G33640.1.

PTM databases

iPTMnetiQ6DR03.

Proteomic databases

PaxDbiQ6DR03.
PRIDEiQ6DR03.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G33640.1; AT2G33640.1; AT2G33640.
GeneIDi817930.
GrameneiAT2G33640.1; AT2G33640.1; AT2G33640.
KEGGiath:AT2G33640.

Organism-specific databases

AraportiAT2G33640.
TAIRilocus:2051068. AT2G33640.

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
HOGENOMiHOG000242421.
InParanoidiQ6DR03.
KOiK20027.
OMAiYVAISVY.
OrthoDBiEOG093606N7.
PhylomeDBiQ6DR03.

Enzyme and pathway databases

BRENDAi2.3.1.225. 399.

Miscellaneous databases

PROiPR:Q6DR03.

Gene expression databases

ExpressionAtlasiQ6DR03. baseline and differential.
GenevisibleiQ6DR03. AT.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
PROSITEiView protein in PROSITE
PS50216. DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiZDHC3_ARATH
AccessioniPrimary (citable) accession number: Q6DR03
Secondary accession number(s): O22814, Q8L8C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: August 16, 2004
Last modified: April 12, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.