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Protein
Submitted name:

High molecular weight kininogen II

Gene

Kng2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
High molecular weight kininogen IIImported
Gene namesi
Name:Kng2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:3027157. Kng2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 634611Sequence analysisPRO_5004272257Add
BLAST

Proteomic databases

PaxDbiQ6DMP4.
PeptideAtlasiQ6DMP4.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097623.

Structurei

3D structure databases

ProteinModelPortaliQ6DMP4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini28 – 131104Cystatin kininogen-typeInterPro annotationAdd
BLAST
Domaini150 – 253104Cystatin kininogen-typeInterPro annotationAdd
BLAST
Domaini262 – 365104Cystatin kininogen-typeInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IKIQ. Eukaryota.
ENOG4111ZQ8. LUCA.
HOVERGENiHBG006224.

Family and domain databases

InterProiIPR000010. Cystatin_dom.
IPR002395. Kininogen.
IPR027358. Kininogen-type_cystatin_dom.
IPR018073. Prot_inh_cystat_CS.
[Graphical view]
PfamiPF00031. Cystatin. 3 hits.
[Graphical view]
PRINTSiPR00334. KININOGEN.
SMARTiSM00043. CY. 3 hits.
[Graphical view]
PROSITEiPS00287. CYSTATIN. 1 hit.
PS51647. CYSTATIN_KININOGEN. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6DMP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLITTLLLC SGLLLTLTQG EEAQEIDCND EAVFQAVDAS LKKLNARLQS
60 70 80 90 100
GNQFVLYRVT KRAKMDGSAT FYSFNYQIKE GNCSAQRGLA WQDCDFKDSE
110 120 130 140 150
EAATGECTAT MGKKENKFFI VTQTCKITPG KGPIVTEEYH CASCVHPISA
160 170 180 190 200
DNPDLEPVLK HAIEYFNNNT GHSHLFALRE VKSAQGQVVG GLNFDIIYTI
210 220 230 240 250
VQTNCSKERF PSLRGDCVAL PNGDGGECRG NAFLDTDNKI EDFTQSCDLH
260 270 280 290 300
PGDDLVEALP KPCPPELKEV LGHSIAQLNT ENDHPFYFKI DTVKKATSQV
310 320 330 340 350
VAGTNYVIEF IARETKCSKE SNTELTEDCE IKHLGQSLDC NANVYMRPWE
360 370 380 390 400
NKVIPTVKCQ ALDKTIPIRR RPPGFSPFRS AKVQETKAGT TVSPPYIVRE
410 420 430 440 450
QKEGNGWLNE KQIKAKNHSG HKYGHDHAHW SPRRHGLGHG HQKPHGLGHG
460 470 480 490 500
HRLKLDYLRH QREDGSDHTH TEGHGYGHGH GHGHGHGHSH GLGHGHDKQT
510 520 530 540 550
NKDKSSVKQT AQRTEPLASS SEYSTTSTQM QGRTEGPTLT PPRAQPTVTS
560 570 580 590 600
SGFQDSDFIE DVVAITPPYD TGAPDDLIPD IHVQPDSLSF KLISDFPEAT
610 620 630
SQKCPGRPWK PASWKDPNTE TTEFSDFDLL DVLS
Length:634
Mass (Da):70,178
Last modified:August 16, 2004 - v1
Checksum:i5ABCA2F23F0846B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY660572 mRNA. Translation: AAT52205.1.
UniGeneiMm.440414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY660572 mRNA. Translation: AAT52205.1.
UniGeneiMm.440414.

3D structure databases

ProteinModelPortaliQ6DMP4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097623.

Proteomic databases

PaxDbiQ6DMP4.
PeptideAtlasiQ6DMP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:3027157. Kng2.

Phylogenomic databases

eggNOGiENOG410IKIQ. Eukaryota.
ENOG4111ZQ8. LUCA.
HOVERGENiHBG006224.

Miscellaneous databases

ChiTaRSiKng2. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR000010. Cystatin_dom.
IPR002395. Kininogen.
IPR027358. Kininogen-type_cystatin_dom.
IPR018073. Prot_inh_cystat_CS.
[Graphical view]
PfamiPF00031. Cystatin. 3 hits.
[Graphical view]
PRINTSiPR00334. KININOGEN.
SMARTiSM00043. CY. 3 hits.
[Graphical view]
PROSITEiPS00287. CYSTATIN. 1 hit.
PS51647. CYSTATIN_KININOGEN. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6DMP4_MOUSE
AccessioniPrimary (citable) accession number: Q6DMP4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.