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Protein
Submitted name:

Potassium voltage-gated channel splice variant erg1b

Gene

Kcnh2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. voltage-gated potassium channel activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel splice variant erg1bImported
Submitted name:
Potassium voltage-gated channel, subfamily H (Eag-related), member 2, isoform CRA_bImported
Gene namesi
Name:Kcnh2Imported
ORF Names:rCG_24426Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621414. Kcnh2.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriQ6DKY7.

Family & Domainsi

Sequence similaritiesi

Contains cyclic nucleotide-binding domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOGENOMiHOG000230793.
HOVERGENiHBG052232.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR003938. K_chnl_volt-dep_EAG/ELK/ERG.
IPR003967. K_chnl_volt-dep_ERG.
IPR030172. KCNH2.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PANTHERiPTHR10217:SF468. PTHR10217:SF468. 1 hit.
PfamiPF00027. cNMP_binding. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01463. EAGCHANLFMLY.
PR01470. ERGCHANNEL.
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6DKY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAIPAGKESR TGALQTRAQK GRVRRAVRIS SLVAQEVLSL GADVLPEYKL
60 70 80 90 100
QAPRIHRWTI LHYSPFKAVW DWLILLLVIY TAVFTPYSAA FLLKETEDGS
110 120 130 140 150
QAPDCGYACQ PLAVVDLLVD IMFIVDILIN FRTTYVNANE EVVSHPGRIA
160 170 180 190 200
VHYFKGWFLI DMVAAIPFDL LIFGSGSEEL IGLLKTARLL RLVRVARKLD
210 220 230 240 250
RYSEYGAAVL FLLMCTFALI AHWLACIWYA IGNMEQPHMD SHIGWLHNLG
260 270 280 290 300
DQIGKPYNSS GLGGPSIKDK YVTALYFTFS SLTSVGFGNV SPNTNSEKIF
310 320 330 340 350
SICVMLIGSL MYASIFGNVS AIIQRLYSGT ARYHTQMLRV REFIRFHQIP
360 370 380 390 400
NPLRQRLEEY FQHAWSYTNG IDMNAVLKGF PECLQADICL HLNRSLLQHC
410 420 430 440 450
KPFRGATKGC LRALAMKFKT THAPPGDTLV HAGDLLTALY FISRGSIEIL
460 470 480 490 500
RGDVVVAILG KNDIFGEPLN LYARPGKSNG DVRALTYCDL HKIHRDDLLE
510 520 530 540 550
VLDMYPEFSD HFWSSLEITF NLRDTNMIPG SPSSAELESG FNRQRKRKLS
560 570 580 590 600
FRRRTDKDTE QPGEVSALGQ GPARVGPGPS CRGQPGGPWG ESPSSGPSSP
610 620 630 640 650
ESSEDEGPGR SSSPLRLVPF SSPRPPGDSP GGEPLTEDGE KSSDTCNPLS
660 670 680 690 700
GAFSGVSNIF SFWGDSRGRQ YQELPRCPAP APSLLNIPLS SPGRRSRGDV
710 720 730 740 750
ESRLDALQRQ LNRLETRLSA DMATVLQLLQ RQMTLVPPAY SAVTTPGPGP
760 770 780 790 800
TSTSPLLPVG PVPTLTLDSL SQVSQFVAFE ELPAGAPELP QDGPTRRLSL
810 820
PGQLGALTSQ PLHRHGSDPG S
Length:821
Mass (Da):90,240
Last modified:August 16, 2004 - v1
Checksum:i23270A284A37A98E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY669863 mRNA. Translation: AAT74902.1.
CH474020 Genomic DNA. Translation: EDL99379.1.
RefSeqiXP_008760852.1. XM_008762630.1.
UniGeneiRn.10970.

Genome annotation databases

GeneIDi117018.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY669863 mRNA. Translation: AAT74902.1.
CH474020 Genomic DNA. Translation: EDL99379.1.
RefSeqiXP_008760852.1. XM_008762630.1.
UniGeneiRn.10970.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi117018.

Organism-specific databases

RGDi621414. Kcnh2.

Phylogenomic databases

HOGENOMiHOG000230793.
HOVERGENiHBG052232.

Gene expression databases

GenevestigatoriQ6DKY7.

Family and domain databases

Gene3Di2.60.120.10. 2 hits.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR003938. K_chnl_volt-dep_EAG/ELK/ERG.
IPR003967. K_chnl_volt-dep_ERG.
IPR030172. KCNH2.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PANTHERiPTHR10217:SF468. PTHR10217:SF468. 1 hit.
PfamiPF00027. cNMP_binding. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01463. EAGCHANLFMLY.
PR01470. ERGCHANNEL.
SMARTiSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: PituitaryImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.

Entry informationi

Entry nameiQ6DKY7_RAT
AccessioniPrimary (citable) accession number: Q6DKY7
Entry historyi
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: March 4, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.