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Q6DKY7 (Q6DKY7_RAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Potassium voltage-gated channel, subfamily H (Eag-related), member 2, isoform CRA_b EMBL EDL99379.1
Gene names
Name:Kcnh2 RGD 621414 EMBL AAT74902.1
ORF Names:rCG_24426 EMBL EDL99379.1
OrganismRattus norvegicus (Rat)
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length821 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains cyclic nucleotide-binding domain. SAAS SAAS000595

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS000595
   Molecular functionIon channel SAAS SAAS000595 RuleBase RU003378
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionvoltage-gated potassium channel activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q6DKY7 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 23270A284A37A98E

FASTA82190,240
        10         20         30         40         50         60 
MAIPAGKESR TGALQTRAQK GRVRRAVRIS SLVAQEVLSL GADVLPEYKL QAPRIHRWTI 

        70         80         90        100        110        120 
LHYSPFKAVW DWLILLLVIY TAVFTPYSAA FLLKETEDGS QAPDCGYACQ PLAVVDLLVD 

       130        140        150        160        170        180 
IMFIVDILIN FRTTYVNANE EVVSHPGRIA VHYFKGWFLI DMVAAIPFDL LIFGSGSEEL 

       190        200        210        220        230        240 
IGLLKTARLL RLVRVARKLD RYSEYGAAVL FLLMCTFALI AHWLACIWYA IGNMEQPHMD 

       250        260        270        280        290        300 
SHIGWLHNLG DQIGKPYNSS GLGGPSIKDK YVTALYFTFS SLTSVGFGNV SPNTNSEKIF 

       310        320        330        340        350        360 
SICVMLIGSL MYASIFGNVS AIIQRLYSGT ARYHTQMLRV REFIRFHQIP NPLRQRLEEY 

       370        380        390        400        410        420 
FQHAWSYTNG IDMNAVLKGF PECLQADICL HLNRSLLQHC KPFRGATKGC LRALAMKFKT 

       430        440        450        460        470        480 
THAPPGDTLV HAGDLLTALY FISRGSIEIL RGDVVVAILG KNDIFGEPLN LYARPGKSNG 

       490        500        510        520        530        540 
DVRALTYCDL HKIHRDDLLE VLDMYPEFSD HFWSSLEITF NLRDTNMIPG SPSSAELESG 

       550        560        570        580        590        600 
FNRQRKRKLS FRRRTDKDTE QPGEVSALGQ GPARVGPGPS CRGQPGGPWG ESPSSGPSSP 

       610        620        630        640        650        660 
ESSEDEGPGR SSSPLRLVPF SSPRPPGDSP GGEPLTEDGE KSSDTCNPLS GAFSGVSNIF 

       670        680        690        700        710        720 
SFWGDSRGRQ YQELPRCPAP APSLLNIPLS SPGRRSRGDV ESRLDALQRQ LNRLETRLSA 

       730        740        750        760        770        780 
DMATVLQLLQ RQMTLVPPAY SAVTTPGPGP TSTSPLLPVG PVPTLTLDSL SQVSQFVAFE 

       790        800        810        820 
ELPAGAPELP QDGPTRRLSL PGQLGALTSQ PLHRHGSDPG S 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY669863 mRNA. Translation: AAT74902.1.
CH474020 Genomic DNA. Translation: EDL99379.1.
UniGeneRn.10970.

3D structure databases

SMRQ6DKY7. Positions 230-271.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

RGD621414. Kcnh2.

Phylogenomic databases

HOGENOMHOG000230793.
HOVERGENHBG052232.

Gene expression databases

GenevestigatorQ6DKY7.

Family and domain databases

Gene3D2.60.120.10. 2 hits.
InterProIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR003938. K_chnl_volt-dep_EAG/ELK/ERG.
IPR003967. K_chnl_volt-dep_ERG.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamPF00027. cNMP_binding. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR01463. EAGCHANLFMLY.
PR01470. ERGCHANNEL.
SMARTSM00100. cNMP. 1 hit.
[Graphical view]
SUPFAMSSF51206. SSF51206. 1 hit.
PROSITEPS50042. CNMP_BINDING_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6DKY7_RAT
AccessionPrimary (citable) accession number: Q6DKY7
Entry history
Integrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)