Reviewed, UniProtKB/Swiss-Prot Q6DKI1 (RL7L_HUMAN)

Names and origin

Protein names

Recommended name:
    60S ribosomal protein L7-like 1

Gene names

Name:

RPL7L1

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein L30P family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct structural constituent of ribosome Inferred from electronic annotation. Source: InterPro transcription regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ARRB1	P49407	1	EBI-1052408,EBI-743313
ARRB2	P32121	1	EBI-1052408,EBI-714559

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 246	246	60S ribosomal protein L7-like 1		PRO_0000104659
Experimental info
	Sequence conflict	191	1	E → G in AAH58020. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q6DKI1-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 2A90B350255BF618	FASTA	246	28,661
	10 20 30 40 50 60 MAEQEQRKIP LVPENLLKKR KAYQALKATQ AKQALLAKKE QKKGKGLRFK RLESFLHDSW 70 80 90 100 110 120 RQKRDKVRLR RLEVKPHALE LPDKHSLAFV VRIERIDGVS LLVQRTIARL RLKKIFSGVF 130 140 150 160 170 180 VKVTPQNLKM LRIVEPYVTW GFPNLKSVRE LILKRGQAKV KNKTIPLTDN TVIEEHLGKF 190 200 210 220 230 240 GVICLEDLIH EIAFPGKHFQ EISWFLCPFH LSVARHATKN RVGFLKEMGT PGYRGERINQ LIRQLN

References

[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]	"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed: 14574404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Eye.
[4]	Colinge J., Superti-Furga G., Bennett K.L. Submitted (OCT-2008) to UniProtKB Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK291949 mRNA. Translation: BAF84638.1. AL035587 Genomic DNA. Translation: CAI21486.1. BC058020 mRNA. Translation: AAH58020.1. BC073890 mRNA. Translation: AAH73890.1.
IPI	IPI00456940.
RefSeq	NP_940888.2.
UniGene	Hs.520133
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q6DKI1. 2 interactions.
STRING	Q6DKI1.
Proteomic databases
PRIDE	Q6DKI1.
Genome annotation databases
Ensembl	ENST00000304734; ENSP00000346063; ENSG00000146223; Homo sapiens. [Genome view] ENST00000493763; ENSP00000418221; ENSG00000146223; Homo sapiens. [Genome view]
GeneID	285855.
KEGG	hsa:285855.
UCSC	uc003osq.1. human.
Organism-specific databases
CTD	285855.
GeneCards	GC05P142693. GC06P042956. GC16P011028.
HGNC	HGNC:21370. RPL7L1.
PharmGKB	PA134977157.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG13150.
HOGENOM	HBG618766.
HOVERGEN	Q6DKI1.
InParanoid	Q6DKI1.
OMA	FVIRMER.
OrthoDB	EOG976NJH.
PhylomeDB	Q6DKI1.
Gene expression databases
ArrayExpress	Q6DKI1.
Bgee	Q6DKI1.
CleanEx	HS_RPL7L1.
Genevestigator	Q6DKI1.
GermOnline	ENSG00000146223. Homo sapiens.
Family and domain databases
InterPro	IPR018038. Ribosomal_L30_CS. IPR016082. Ribosomal_L30_ferredoxin-like. IPR012988. Ribosomal_L30_N. IPR000517. Ribosomal_L30p/L7e_cons-reg. IPR005998. Ribosomal_L7_euk. [Graphical view]
Pfam	PF00327. Ribosomal_L30. 1 hit. PF08079. Ribosomal_L30_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01310. L7. 1 hit.
PROSITE	PS00634. RIBOSOMAL_L30. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	95830.

Entry information

Entry name

RL7L_HUMAN

Accession

Primary (citable) accession number: Q6DKI1
Secondary accession number(s): A8K7D4, Q5TFZ5, Q6PEK3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 27, 2004
Last sequence update:	August 16, 2004
Last modified:	February 9, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.