Q6DKE1 (CYC2_XENLA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c, testis-specific

Gene names

Name:

cyct

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain By similarity.
Subcellular location	Mitochondrion intermembrane space By similarity. Note: Loosely associated with the inner membrane By similarity.
Post-translational modification	Binds 1 heme group per subunit By similarity.
Sequence similarities	Belongs to the cytochrome c family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	Heme Iron Metal-binding
PTM	Acetylation
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial intermembrane space Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 105	104	Cytochrome c, testis-specific		PRO_0000266017
Sites
	Metal binding	19	1	Iron (heme axial ligand) By similarity
	Metal binding	81	1	Iron (heme axial ligand) By similarity
	Binding site	15	1	Heme (covalent) By similarity
	Binding site	18	1	Heme (covalent) By similarity
Amino acid modifications
	Modified residue	2	1	N-acetylglycine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6DKE1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 2EEA3D49783A526B	FASTA	105	11,695
	10 20 30 40 50 60 MGDVEKGKKV FVQKCSQCHT VEKGGKHKTG PNLHGLFGRK TGQAEGFSYT DANKNKGIVW 70 80 90 100 DEDTLMVYLE NPKKYIPGTK MIFAGIKKKG ERQDLIAYLK QSTSS

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney.

Web resources

Protein Spotlight

Life shuttle - Issue 76 of November 2006

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC074190 mRNA. Translation: AAH74190.1.
RefSeq	NP_001086101.1. NM_001092632.1.
UniGene	Xl.24213.
3D structure databases
ProteinModelPortal	Q6DKE1.
SMR	Q6DKE1. Positions 2-104.
ModBase	Search...
Proteomic databases
PRIDE	Q6DKE1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	444530.
KEGG	xla:444530.
Organism-specific databases
CTD	54205.
Xenbase	XB-GENE-971594. cycs.
Phylogenomic databases
HOVERGEN	HBG003023.
KO	K08738.
Family and domain databases
InterPro	IPR002327. Cyt_c_1A/1B. IPR009056. Cyt_c_dom. IPR003088. Cyt_c_I. [Graphical view]
PANTHER	PTHR11961. PTHR11961. 1 hit.
Pfam	PF00034. Cytochrom_C. 1 hit. [Graphical view]
PRINTS	PR00604. CYTCHRMECIAB.
SUPFAM	SSF46626. Cytochrome_c. 1 hit.
PROSITE	PS51007. CYTC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYC2_XENLA

Accession

Primary (citable) accession number: Q6DKE1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	January 23, 2007
Last modified:	May 29, 2013
This is version 61 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program