Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6DJN3 (P3F4B_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
POU domain, class 3, transcription factor 4-B
Gene names
Name:pou3f4-b
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Transcriptional activator. Induces neural-specific gene expression to act as a key regulator of neural differentiation By similarity. UniProtKB P31364

Subcellular location

Nucleus By similarity UniProtKB P49335.

Sequence similarities

Belongs to the POU transcription factor family. Class-3 subfamily.

Contains 1 homeobox DNA-binding domain.

Contains 1 POU-specific domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 356356POU domain, class 3, transcription factor 4-B
PRO_0000389616

Regions

Domain181 – 25575POU-specific
DNA binding273 – 33260Homeobox

Sequences

Sequence LengthMass (Da)Tools
Q6DJN3 [UniParc].

Last modified August 16, 2004. Version 1.
Checksum: 9D32C537C04980B7

FASTA35639,174
        10         20         30         40         50         60 
MATAASNPYS ILSSSSLVHA DSAVMQQGSP FRNPQKLLQS DYLQGIPSNG HPLGHHWVTS 

        70         80         90        100        110        120 
LSDANPWSSL ASSPLDQQDI KPGREDLQLG AIIHHRSPHV SHHSPHNNHP NTWGASPVHN 

       130        140        150        160        170        180 
SSGQPINVYS QPGFTVSGML DHGGLTPPPP SGTTQSLHPV LREATDHGDL GSHHCHDHSD 

       190        200        210        220        230        240 
EETPTSDELE QFAKLFKQRR IKLGFTQADV GLALGTLYGN VFSQTTICRF EALQLSFKNM 

       250        260        270        280        290        300 
CKLKPLLNKW LEEADSSTGS PTSIDKIAAQ GRKRKKRTSI EVSVKGVLET HFLKCPKPAA 

       310        320        330        340        350 
LEISSLADSL QLEKEVVRVW FCNRRQKEKR MTPPGDPQQH EIYSHSVKTD TSCNEL 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC075142 mRNA. Translation: AAH75142.1.
RefSeqNP_001086347.1. NM_001092878.1.
UniGeneXl.81580.

3D structure databases

ProteinModelPortalQ6DJN3.
SMRQ6DJN3. Positions 187-333.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID444776.
KEGGxla:444776.

Organism-specific databases

CTD444776.

Phylogenomic databases

HOVERGENHBG053120.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
IPR016362. Transcription_factor_POU.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PIRSFPIRSF002629. Transcription_factor_POU. 1 hit.
PRINTSPR00028. POUDOMAIN.
SMARTSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP3F4B_XENLA
AccessionPrimary (citable) accession number: Q6DJN3
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2009
Last sequence update: August 16, 2004
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families