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Protein
Submitted name:

Hedgehog interacting protein

Gene

hhip

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Hedgehog interacting proteinImported
Gene namesi
Name:hhipImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-487499. hhip.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi588 ↔ 598PROSITE-ProRule annotation
Disulfide bondi606 ↔ 615PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiQ6DIG3.

Structurei

3D structure databases

ProteinModelPortaliQ6DIG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini584 – 616EGF-likeInterPro annotationAdd BLAST33

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IEIH. Eukaryota.
ENOG410ZT1I. LUCA.
HOGENOMiHOG000008644.
HOVERGENiHBG051901.
KOiK06231.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
InterProiView protein in InterPro
IPR011042. 6-blade_b-propeller_TolB-like.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR018143. Folate_rcpt-like.
IPR012938. Glc/Sorbosone_DH.
IPR011041. Quinoprot_gluc/sorb_DH.
PfamiView protein in Pfam
PF03024. Folate_rec. 1 hit.
PF07995. GSDH. 1 hit.
SMARTiView protein in SMART
SM00181. EGF. 2 hits.
SUPFAMiSSF50952. SSF50952. 2 hits.
PROSITEiView protein in PROSITE
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DIG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRISSTQVK DPKHLRSNCS FLPFARTIAK SSTTHAEARY QIISVTNNTE
60 70 80 90 100
CAKLVEEIRC AQCSPHAQNL FHASERSETS EKQLFLPALC KDYCKEFYYT
110 120 130 140 150
CRGQIPGLLQ TSADEFCFYH GMKDSGLCFP DFPRKQMRGP ASNYLDQMED
160 170 180 190 200
YDKVEEISRK HKHNCYCIQE VVRGLRQPVG AMHSGDGSQR LFILEKEGYI
210 220 230 240 250
KILTPEGDLI KEPFLDVHKV VQSGIKGGDE RGLLGLAFHP NYKKNGKLYV
260 270 280 290 300
SYTTNQERWA SGPHDHILRV VEYTVSRKNP SQVDVRTERI FLEVAELHRK
310 320 330 340 350
HLGGQLLFGP DGFLYIFLGD GMITIDDMEE MDGLSDFTGS VLRVDVDIDG
360 370 380 390 400
CSALYSIPRS NPHFNSTNQP PEIFAHGLHN PGRCTVDHLS KDSNMNLTIL
410 420 430 440 450
CSDSSTKNRS SARILQIVKG KDYENDPPLL EFKPLSSGHM VGGFIYRGCQ
460 470 480 490 500
SERLYGSYVF GDRYGNFVSL HQNQVTKHWQ EKPLCLGSGS SCRAPFTGHI
510 520 530 540 550
LGFGEDELGE VYILSSSKSM TQSHSGKIYK IIDPKRPTVP EECKRPLMPA
560 570 580 590 600
QPLASECSRH CRNGHCTPTG KCCCTQGWEG EFCRIAKCEP ECRHGGVCVR
610 620 630 640
PNKCLCKKGY LGPQCEQMDR NVRRVARAGI LDQIIDVTSY LLDLTSYIV
Length:649
Mass (Da):73,075
Last modified:August 16, 2004 - v1
Checksum:iAA1F37E50DD95B55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC075579 mRNA. Translation: AAH75579.1.
RefSeqiNP_001007191.1. NM_001007190.1.
UniGeneiStr.71500.

Genome annotation databases

GeneIDi448466.
KEGGixtr:448466.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6DIG3_XENTR
AccessioniPrimary (citable) accession number: Q6DIG3
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: July 5, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation