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Protein

Sorting nexin

Gene

snx5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in several stages of intracellular trafficking.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • blood vessel morphogenesis Source: ZFIN
  • endocytosis Source: GO_Central
  • gliogenesis Source: ZFIN
  • hemopoiesis Source: ZFIN
  • intracellular protein transport Source: InterPro
  • Notch signaling pathway Source: ZFIN
  • pinocytosis Source: InterPro
  • retina development in camera-type eye Source: ZFIN
  • vesicle organization Source: GO_Central

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Enzyme and pathway databases

ReactomeiR-DRE-432722 Golgi Associated Vesicle Biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Sorting nexinUniRule annotation
Gene namesi
Name:snx5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-040426-2857 snx5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000020442

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000018231

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 167PXInterPro annotationAdd BLAST167

Sequence similaritiesi

Belongs to the sorting nexin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1660 Eukaryota
ENOG410XPZY LUCA
GeneTreeiENSGT00910000144062
HOVERGENiHBG000716
OMAiHEDFIWL
OrthoDBiEOG091G08NT
TreeFamiTF313698

Family and domain databases

Gene3Di1.20.1270.60, 1 hit
3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR001683 Phox
IPR036871 PX_dom_sf
IPR028654 SNX5
IPR014637 SNX5/SNX6/SNX32
IPR015404 Vps5_C
PANTHERiPTHR10555:SF6 PTHR10555:SF6, 1 hit
PfamiView protein in Pfam
PF00787 PX, 1 hit
PF09325 Vps5, 1 hit
PIRSFiPIRSF036924 Snx5_Snx6, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50195 PX, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DI32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSISEDSDK EKARSVSVDL NNDASLLIDI PDALCERDKV KFTVHTKTTL
60 70 80 90 100
SSFQKPDFSV PRQHEDFIWL HDAIVETEEY AGLIIPPAPP KPDFEGPREK
110 120 130 140 150
MHKLGEGESS MTKEEYAKMK QELEAEYLAV FKKTVQVHEV FLQRLSSHPS
160 170 180 190 200
FSKDRNFHIF LEYDQDLSVR RKNAKEMFGG FFKNMVKTAD EVLISGVKEV
210 220 230 240 250
DEFFEQEKTF LLDYSNKIKD STAKAEKMTR SHKNVADDYN HISGALNSVA
260 270 280 290 300
ADNNSAFKKH LEKCVEVFEK LRKVEDRVAS DQELKLTELL RYYTRDIQAA
310 320 330 340 350
KDLLYRRARA LADYENSNKA LDKARLKGKD VPQAEENQKQ CLQKFDRLSE
360 370 380 390
SGKKELTSFK ARRVVAFRKN LIEMTELEIK HAKNSMSTLQ GSIELLKSN
Length:399
Mass (Da):45,934
Last modified:August 16, 2004 - v1
Checksum:i03B8EFF4A18A3771
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005372 Genomic DNA No translation available.
BC075758 mRNA Translation: AAH75758.1
UniGeneiDr.6495

Genome annotation databases

EnsembliENSDART00000020350; ENSDARP00000018231; ENSDARG00000020442

Similar proteinsi

Entry informationi

Entry nameiQ6DI32_DANRE
AccessioniPrimary (citable) accession number: Q6DI32
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: June 20, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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