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Protein

Sorting nexin

Gene

snx5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in several stages of intracellular trafficking.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • blood vessel morphogenesis Source: ZFIN
  • endocytosis Source: GO_Central
  • gliogenesis Source: ZFIN
  • hemopoiesis Source: ZFIN
  • intracellular protein transport Source: InterPro
  • Notch signaling pathway Source: ZFIN
  • pinocytosis Source: InterPro
  • retina development in camera-type eye Source: ZFIN
  • vesicle organization Source: GO_Central

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sorting nexinUniRule annotation
Gene namesi
Name:snx5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-040426-2857. snx5.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000020442.

Interactioni

Protein-protein interaction databases

MINTiMINT-2841455.
STRINGi7955.ENSDARP00000018231.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 167PXInterPro annotationAdd BLAST167

Sequence similaritiesi

Belongs to the sorting nexin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1660. Eukaryota.
ENOG410XPZY. LUCA.
GeneTreeiENSGT00900000140943.
HOVERGENiHBG000716.
OMAiHEDFIWL.
OrthoDBiEOG091G08NT.
TreeFamiTF313698.

Family and domain databases

Gene3Di1.20.1270.60. 1 hit.
3.30.1520.10. 1 hit.
InterProiView protein in InterPro
IPR027267. AH/BAR_dom_sf.
IPR001683. Phox.
IPR036871. PX_dom_sf.
IPR028654. SNX5.
IPR014637. SNX5/SNX6/SNX32.
IPR015404. Vps5_C.
PANTHERiPTHR10555:SF6. PTHR10555:SF6. 1 hit.
PfamiView protein in Pfam
PF00787. PX. 1 hit.
PF09325. Vps5. 1 hit.
PIRSFiPIRSF036924. Snx5_Snx6. 1 hit.
SUPFAMiSSF103657. SSF103657. 1 hit.
SSF64268. SSF64268. 1 hit.
PROSITEiView protein in PROSITE
PS50195. PX. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DI32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSISEDSDK EKARSVSVDL NNDASLLIDI PDALCERDKV KFTVHTKTTL
60 70 80 90 100
SSFQKPDFSV PRQHEDFIWL HDAIVETEEY AGLIIPPAPP KPDFEGPREK
110 120 130 140 150
MHKLGEGESS MTKEEYAKMK QELEAEYLAV FKKTVQVHEV FLQRLSSHPS
160 170 180 190 200
FSKDRNFHIF LEYDQDLSVR RKNAKEMFGG FFKNMVKTAD EVLISGVKEV
210 220 230 240 250
DEFFEQEKTF LLDYSNKIKD STAKAEKMTR SHKNVADDYN HISGALNSVA
260 270 280 290 300
ADNNSAFKKH LEKCVEVFEK LRKVEDRVAS DQELKLTELL RYYTRDIQAA
310 320 330 340 350
KDLLYRRARA LADYENSNKA LDKARLKGKD VPQAEENQKQ CLQKFDRLSE
360 370 380 390
SGKKELTSFK ARRVVAFRKN LIEMTELEIK HAKNSMSTLQ GSIELLKSN
Length:399
Mass (Da):45,934
Last modified:August 16, 2004 - v1
Checksum:i03B8EFF4A18A3771
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005372 Genomic DNA. No translation available.
BC075758 mRNA. Translation: AAH75758.1.
UniGeneiDr.6495.

Genome annotation databases

EnsembliENSDART00000020350; ENSDARP00000018231; ENSDARG00000020442.

Similar proteinsi

Entry informationi

Entry nameiQ6DI32_DANRE
AccessioniPrimary (citable) accession number: Q6DI32
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 22, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported