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Protein
Submitted name:

Hydroxyacyl-CoA dehydrogenase

Gene

hadh

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei68Coenzyme AUniRule annotation1
Binding sitei75Coenzyme AUniRule annotation1
Binding sitei144Coenzyme AUniRule annotation1
Sitei165Important for catalytic activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-77310 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
R-DRE-77346 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
R-DRE-77348 Beta oxidation of octanoyl-CoA to hexanoyl-CoA
R-DRE-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA
R-DRE-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA

Names & Taxonomyi

Protein namesi
Submitted name:
Hydroxyacyl-CoA dehydrogenaseImported
Submitted name:
Hydroxyacyl-Coenzyme A dehydrogenaseImported
Gene namesi
Name:hadhImported
Synonyms:hadhscImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-040801-261 hadh

Expressioni

Gene expression databases

BgeeiENSDARG00000030765

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000050602

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 2093HCDH_NInterPro annotationAdd BLAST186
Domaini211 – 3073HCDHInterPro annotationAdd BLAST97

Phylogenomic databases

eggNOGiKOG2304 Eukaryota
COG1250 LUCA
GeneTreeiENSGT00880000137923
HOGENOMiHOG000141498
HOVERGENiHBG000832
KOiK00022
OMAiMAHPMGP
OrthoDBiEOG091G089P
TreeFamiTF300886

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR022694 3-OHacyl-CoA_DH
IPR006180 3-OHacyl-CoA_DH_CS
IPR006176 3-OHacyl-CoA_DH_NAD-bd
IPR006108 3HC_DH_C
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF00725 3HCDH, 1 hit
PF02737 3HCDH_N, 1 hit
PIRSFiPIRSF000105 HCDH, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00067 3HCDH, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DI22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFVTRQFSR SFSSSQALHH TIKHVTVIGG GLMGAGIAQV AASTGHSVVL
60 70 80 90 100
VDTSADILNK SAKGIENSLK RVAKKKFAEK PEDGEAFVQK VLKNVSTSTD
110 120 130 140 150
AASVVHGTDL VVEAIVENLK VKQDLFGALD KVAPEHTIFA SNTSSLPIAD
160 170 180 190 200
IASCTARLDR FGGLHFFNPV PMMKLVEVIK TPATSQQTFD ALLEFSKALG
210 220 230 240 250
KHPVSCKDTP GFIVNRLLVP YMLEAVRLHE RGHGSKEDID VAMKLGAGYP
260 270 280 290 300
MGPFELLDYV GLDTSKFIID GWHAKDPDNP LFAPSPLLNK LVSEGKLGKK

TGEGFYKHK
Length:309
Mass (Da):33,336
Last modified:August 16, 2004 - v1
Checksum:i893A07AB0778890B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572104 Genomic DNA No translation available.
BC075768 mRNA Translation: AAH75768.1
RefSeqiNP_001003515.1, NM_001003515.1
UniGeneiDr.34131

Genome annotation databases

EnsembliENSDART00000050603; ENSDARP00000050602; ENSDARG00000030765
GeneIDi445121
KEGGidre:445121

Similar proteinsi

Entry informationi

Entry nameiQ6DI22_DANRE
AccessioniPrimary (citable) accession number: Q6DI22
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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