Unreviewed, UniProtKB/TrEMBL Q6DHZ8 (Q6DHZ8_HUMAN)

Names and origin

Protein names

Submitted name:
    Activity-dependent neuroprotector homeobox EMBL AAH75794.1

Gene names

Name:

ADNP EMBL AAH75794.1

Organism

Homo sapiens (Human) EMBL AAH75794.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1102 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location

Nucleus By similarity. RuleBase RU000682V4

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682V4
Domain	Homeobox RuleBase RU000682V4
Ligand	DNA-binding RuleBase RU000682V4
Gene Ontology (GO)
Biological process	negative regulation of neuron apoptosis Inferred from electronic annotation. Source: Compara regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular space Inferred from electronic annotation. Source: Compara nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	chromatin binding Inferred from electronic annotation. Source: Compara protein binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6DHZ8-1 [UniParc]. Last modified August 16, 2004. Version 1. Checksum: 2B6984E554DC766A	FASTA	1,102	123,447
	10 20 30 40 50 60 MFQLPVNNLG SLRKARKTVK KILSDIGLEY CKEHIEDFKQ FEPNDFYLKN TTWEDVGLWD 70 80 90 100 110 120 PSLTKNQDYR TKPFCCSACP CSSKFFSAYK SHFRNVHSED FENRILLNCP YCTFNADKKT 130 140 150 160 170 180 LETHIKIFHA PNASAPSSSL STFKDKNKND GLKPKQADSV EQAVYYCKKC TYRDPLYEIV 190 200 210 220 230 240 RKHIYREHFQ HVAAPYIAKA GEKSLNGAVP LGSNAREESS IHCKRCLFMP KSYEALVQHV 250 260 270 280 290 300 IEDHERIGYQ VTAMIGHTNV VVPRSKPLML IAPKPQDKKS MGLPPRIGSL ASGNVRSLPS 310 320 330 340 350 360 QQMVNRLSIP KPNLNSTGVN MMSSVHLQQN NYGVKSVGQG YSVGQSMRLG LGGNAPVSIP 370 380 390 400 410 420 QQSQSVKQLL PSGNGRSYGL GSEQRSQAPA RYSLQSANAS SLSSGQLKSP SLSQSQASRV 430 440 450 460 470 480 LGQSSSKPAA AATGPPPGNT SSTQKWKICT ICNELFPENV YSVHFEKGHK AEKVPAVANY 490 500 510 520 530 540 IMKIHNFTSK CLYCNRYLPT DTLLNHMLIH GLSCPYCRST FNDVEKMAAH MRMVHIDEEM 550 560 570 580 590 600 GPKTDSTLSF DLTLQQGSHT NIHLLVTTYN LRDAPAESVA YHAQNNPPVP PKPQPKVQEK 610 620 630 640 650 660 ADIPVKSSPQ AAVPYKKDVG KTLCPLCFSI LKGPISDALA HHLRERHQVI QTVHPVEKKL 670 680 690 700 710 720 TYKCIHCLGV YTSNMTASTI TLHLVHCRGV GKTQNGQDKT NAPSRLNQSP SLAPVKRTYE 730 740 750 760 770 780 QMEFPLLKKR KLDDDSDSPS FFEEKPEEPV VLALDPKGHE DDSYEARKSF LTKYFNKQPY 790 800 810 820 830 840 PTRREIEKLA ASLWLWKSDI ASHFSNKRKK CVRDCEKYKP GVLLGFNMKE LNKVKHEMDF 850 860 870 880 890 900 DAEWLFENHD EKDSRVNASK TADKKLNLGK EDDSSSDSFE NLEEESNESG SPFDPVFEVE 910 920 930 940 950 960 PKISNDNPEE HVLKVIPEDA SESEEKLDQK EDGSKYETIH LTEEPTKLMH NASDSEVDQD 970 980 990 1000 1010 1020 DVVEWKDGAS PSESGPGSQQ VSDFEDNTCE MKPGTWSDES SQSEDARSSK PAAKKKATMQ 1030 1040 1050 1060 1070 1080 GDREQLKWKN SSYGKVEGFW SKDQSQWKNA SENDERLSNP QIEWQNSTID SEDGEQFDNM 1090 1100 TDGVAEPMHG SLAGVKLSSQ QA

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Placenta EMBL AAH75794.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC075794 mRNA. Translation: AAH75794.1.
IPI	IPI00022215.
UniGene	Hs.570355
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000101126. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:15766. ADNP.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q6DHZ8.
Gene expression databases
ArrayExpress	Q6DHZ8.
Bgee	Q6DHZ8.
Family and domain databases
InterPro	IPR017871. ABC_transporter_CS. IPR001356. Homeobox. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. [Graphical view]
Pfam	PF00046. Homeobox. 1 hit. PF00096. zf-C2H2. 1 hit. [Graphical view]
SMART	SM00389. HOX. 1 hit. SM00355. ZnF_C2H2. 8 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. Uncertain. PS50071. HOMEOBOX_2. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6DHZ8_HUMAN

Accession

Primary (citable) accession number: Q6DHZ8

Entry history

Integrated into UniProtKB/TrEMBL:	August 16, 2004
Last sequence update:	August 16, 2004
Last modified:	March 3, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)