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Protein
Submitted name:

Actin, alpha 2, smooth muscle, aorta

Gene

acta2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • blood circulation Source: ZFIN
  • heart contraction Source: ZFIN
  • mesenchyme migration Source: AgBase
  • positive regulation of gene expression Source: AgBase

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-390522 Striated Muscle Contraction

Names & Taxonomyi

Protein namesi
Submitted name:
Actin, alpha 2, smooth muscle, aortaImported
Gene namesi
Name:acta2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-030131-1229 acta2

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000045180

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000066429

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0676 Eukaryota
COG5277 LUCA
GeneTreeiENSGT00760000118957
HOGENOMiHOG000233340
HOVERGENiHBG003771
KOiK12313
OMAiPXEREIV
OrthoDBiEOG091G08LD
TreeFamiTF354237

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR020902 Actin/actin-like_CS
IPR004001 Actin_CS
PANTHERiPTHR11937 PTHR11937, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 1 hit
PRINTSiPR00190 ACTIN
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit
PROSITEiView protein in PROSITE
PS00406 ACTINS_1, 1 hit
PS00432 ACTINS_2, 1 hit
PS01132 ACTINS_ACT_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6DHS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCDDEESTAL VCDNGSGLCK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG
60 70 80 90 100
QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH SFYNELRVAP
110 120 130 140 150
EEHPTLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA VLSLYASGRT
160 170 180 190 200
TGIVLDSGDG VTHNVPIYEG YALPHAIMRL DLAGRDLTDY LMKILTERGY
210 220 230 240 250
SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK SYELPDGQVI
260 270 280 290 300
TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV
310 320 330 340 350
LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS
360 370
LSTFQQMWIS KQEYDEAGPS IVHRKCF
Length:377
Mass (Da):41,995
Last modified:August 16, 2004 - v1
Checksum:iD8B5F363EA5AD850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO704908 Genomic DNA No translation available.
FP102417 Genomic DNA No translation available.
FQ323121 Genomic DNA No translation available.
BC075896 mRNA Translation: AAH75896.1
RefSeqiNP_997785.2, NM_212620.2
UniGeneiDr.20277

Genome annotation databases

EnsembliENSDART00000066430; ENSDARP00000066429; ENSDARG00000045180
ENSDART00000177923; ENSDARP00000143706; ENSDARG00000045180
GeneIDi322509
KEGGidre:322509

Similar proteinsi

Entry informationi

Entry nameiQ6DHS1_DANRE
AccessioniPrimary (citable) accession number: Q6DHS1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: March 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health