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Protein
Submitted name:

Actin, alpha 2, smooth muscle, aorta

Gene

acta2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • blood circulation Source: ZFIN
  • heart contraction Source: ZFIN
  • mesenchyme migration Source: AgBase
  • positive regulation of gene expression Source: AgBase

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-445355. Smooth Muscle Contraction.

Names & Taxonomyi

Protein namesi
Submitted name:
Actin, alpha 2, smooth muscle, aortaImported
Gene namesi
Name:acta2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-030131-1229. acta2.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000045180.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000066429.

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
GeneTreeiENSGT00760000118957.
HOGENOMiHOG000233340.
HOVERGENiHBG003771.
OMAiPXEREIV.
OrthoDBiEOG091G08LD.
TreeFamiTF354237.

Family and domain databases

InterProiView protein in InterPro
IPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiView protein in Pfam
PF00022. Actin. 1 hit.
PRINTSiPR00190. ACTIN.
SMARTiView protein in SMART
SM00268. ACTIN. 1 hit.
PROSITEiView protein in PROSITE
PS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6DHS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCDDEESTAL VCDNGSGLCK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG
60 70 80 90 100
QKDSYVGDEA QSKRGILTLK YPIEHGIITN WDDMEKIWHH SFYNELRVAP
110 120 130 140 150
EEHPTLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA VLSLYASGRT
160 170 180 190 200
TGIVLDSGDG VTHNVPIYEG YALPHAIMRL DLAGRDLTDY LMKILTERGY
210 220 230 240 250
SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK SYELPDGQVI
260 270 280 290 300
TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV
310 320 330 340 350
LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS
360 370
LSTFQQMWIS KQEYDEAGPS IVHRKCF
Length:377
Mass (Da):41,995
Last modified:August 16, 2004 - v1
Checksum:iD8B5F363EA5AD850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO704908 Genomic DNA. No translation available.
FP102417 Genomic DNA. No translation available.
FQ323121 Genomic DNA. No translation available.
BC075896 mRNA. Translation: AAH75896.1.
RefSeqiNP_997785.2. NM_212620.2.
UniGeneiDr.20277.

Genome annotation databases

EnsembliENSDART00000066430; ENSDARP00000066429; ENSDARG00000045180.
ENSDART00000177923; ENSDARP00000143706; ENSDARG00000045180.
GeneIDi322509.

Similar proteinsi

Entry informationi

Entry nameiQ6DHS1_DANRE
AccessioniPrimary (citable) accession number: Q6DHS1
Entry historyiIntegrated into UniProtKB/TrEMBL: August 16, 2004
Last sequence update: August 16, 2004
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported